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Recruiting NCT03905239

A Procalcitonin-based Algorithm in Adhesion-related Small Bowel Obstruction

Trial Parameters

Condition Small Bowel Obstruction
Sponsor Centre Hospitalier Universitaire, Amiens
Study Type INTERVENTIONAL
Phase N/A
Enrollment 488
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2019-04-01
Completion 2025-10
Interventions
algorithm

Brief Summary

Adhesion-related small bowel obstruction is a common digestive emergency that can be managed either conservatively or surgically. However, the choice between these two approaches can be difficult due to the absence of specific signs. The objective of this study is to evaluate the clinical impact of a procalcitonin-based algorithm.

Eligibility Criteria

Inclusion Criteria: * Uncomplicated acute adhesion-related small bowel obstruction (ASBO) * Adults * Patients able to express consent * Signed written informed consent form * Covered by national health insurance Exclusion Criteria: * Disease-related criteria: * Large bowel obstruction * No previous abdominal surgery * Signs of peritonitis or strangulation requiring emergency surgery) * Obstruction within 4 weeks following previous surgery * Ongoing or history of bowel cancer * Ongoing or in history of inflammatory bowel disease * History of abdominal radiotherapy * Active infection * Contraindication to contrast-enhanced CT scan * Minors * Patient deprived of liberty by administrative or judicial decision or placed under judicial protection (guardianship or supervision) * Pregnancy or breastfeeding

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