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Recruiting NCT05539196

NCT05539196 A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor Complications

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Clinical Trial Summary
NCT ID NCT05539196
Status Recruiting
Phase
Sponsor InSightec
Condition Movement Disorders
Study Type OBSERVATIONAL
Enrollment 60 participants
Start Date 2023-01-23
Primary Completion 2029-07-31

Eligibility & Interventions

Sex All sexes
Min Age 30 Years
Max Age 99 Years
Study Type OBSERVATIONAL
Interventions
Exablate Pallidotomy, Unilateral

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 60 participants in total. It began in 2023-01-23 with a primary completion date of 2029-07-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This registry is a prospective, multicenter, international, single arm, observational post-approval registry with follow-up at 3, 6, and 12 months, and annually for 5 years. The proposed registry will enroll 60 subjects and will be conducted at approximately 10 centers worldwide.

Eligibility Criteria

Inclusion Criteria: * Men and women, age 30 years and older. * Subject undergoing a planned an Exablate procedure for their Parkinson's Disease with Motor Complications per local institution standard of care. * Subject is willing to cooperate with the Registry requirements including compliance with the regimen and completion of all Registry visits. * Subject has signed and received a copy of the approved informed consent form. Exclusion Criteria: * Subject does not agree to participate or is unlikely to participate for the entirety of the Registry.

Contact & Investigator

Central Contact

Kingsley Nwaogu

✉ clinicalresearchquestions@insightec.com

📞 2143048265

Frequently Asked Questions

Who can join the NCT05539196 clinical trial?

This trial is open to participants of all sexes, aged 30 Years or older, up to 99 Years, studying Movement Disorders. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05539196 currently recruiting?

Yes, NCT05539196 is actively recruiting participants. Contact the research team at clinicalresearchquestions@insightec.com for enrollment information.

Where is the NCT05539196 trial being conducted?

This trial is being conducted at Baltimore, United States, New York, United States, Philadelphia, United States, Dallas, United States and 1 additional location.

Who is sponsoring the NCT05539196 clinical trial?

NCT05539196 is sponsored by InSightec. The trial plans to enroll 60 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology