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RecruitingNCT07287124

A Pivotal Study to Evaluate the Clinical Benefit, Performance and Safety of a Totally Implantable Cochlear Implant (TICI) System in Adults

Trial Parameters

ConditionHearing Loss, Bilateral Sensorineural
SponsorCochlear
Study TypeINTERVENTIONAL
PhaseN/A
Enrollment56
SexALL
Min Age18 Years
Max AgeN/A
Start Date2026-04
Completion2027-10
Interventions
Cochlear implant

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Brief Summary

This pivotal study examines the clinical efficacy and safety of an investigational totally implantable cochlear implant (TICI) system. The system includes a microphone placed under the skin to detect speech and sound from the environment, providing the option to hear without any visible external parts. This study will involve adults with sensorineural hearing loss, a type of hearing loss caused by damage to the inner ear or auditory nerve (the nerve that carries sound signals from the ear to the brain). Participants will complete hearing tests and questionnaires to evaluate how well the system works and how it affects their daily life.

Eligibility Criteria

Inclusion Criteria: * Individuals aged 18 years and older at time of consent. * Clinically established sensorineural hearing loss (SNHL) defined by a four frequency (500, 1000, 2000, 4000 Hz) pure-tone average unaided threshold (PTA4) of ≥70 dB HL in the ear to be implanted. * Compromised functional hearing in the aided condition defined as ≤40% correct on a word recognition test in the ear to be implanted. * Clinically established SNHL defined by a four-frequency (500, 1000, 2000 \& 4000 Hz) pure-tone average unaided threshold (PTA4) of ≥30 dB HL in the contralateral ear. * Candidate is a fluent speaker in the language used to assess speech perception performance as determined by the investigator. * Direct access to a compatible Smart Phone. * Willing and able to provide written informed consent. Exclusion Criteria: * Prior cochlear implantation, in either ear, or medical plan for cochlear implantation during the clinical investigation, contralateral to the ear to be implanted. * Cand

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