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Recruiting NCT06712446

NCT06712446 A Pilot Study of Transcranial Magnetic Stimulation Plus Episodic Future Thinking for Methamphetamine Use Disorder

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Clinical Trial Summary
NCT ID NCT06712446
Status Recruiting
Phase
Sponsor The University of Texas Health Science Center, Houston
Condition Methamphetamine Use Disorder
Study Type INTERVENTIONAL
Enrollment 20 participants
Start Date 2025-03-26
Primary Completion 2026-12-31

Trial Parameters

Condition Methamphetamine Use Disorder
Sponsor The University of Texas Health Science Center, Houston
Study Type INTERVENTIONAL
Phase N/A
Enrollment 20
Sex ALL
Min Age 18 Years
Max Age 65 Years
Start Date 2025-03-26
Completion 2026-12-31
Interventions
EFThigh frequency rTMSsham frequency rTMS

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Brief Summary

The purpose of this study is to assess impact of repetitive transcranial magnetic stimulation (rTMS)+Episodic Future Thinking (EFT) vs. sham rTMS+EFT on delay discounting and methamphetamine (MA) demand, on vividness of future positive events during EFT training and on frequency of episodic thinking during the week following EFT training

Eligibility Criteria

Inclusion Criteria: * Meet Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria for primary methamphetamine use disorder * Be fluent in English and able to understand the consent form Exclusion Criteria: * Current DSM-5 diagnosis for any illicit substance use disorder other than methamphetamine and marijuana * Current DSM-5 diagnosis of moderate or greater severity for alcohol and marijuana use disorder * In the opinion of the PI, the presence of any medical, neurological, psychiatric (e.g., psychotic or bipolar disorder), or physical condition, disease, or illness that, may: (a) compromise, interfere, limit, effect or reduce the subject's ability to complete the study; or (b) adversely impact the safety of the subject or the integrity of the data * Has current or recent (within 3 months of potential enrollment) suicidal ideation, suicidal behavior, homicidal ideation or a homicidal plan sufficient to raise subject safety concerns based on the following

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