NCT07341984 A Physiotherapy Intervention Study in Patients With Amyotrophic Lateral Sclerosis (ALS)
| NCT ID | NCT07341984 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Charlotte Vogt |
| Condition | Amyotrophic Lateral Sclerosis |
| Study Type | INTERVENTIONAL |
| Enrollment | 38 participants |
| Start Date | 2025-12-16 |
| Primary Completion | 2027-12-15 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 38 participants in total. It began in 2025-12-16 with a primary completion date of 2027-12-15.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study investigates whether an individualized physiotherapy program, tailored to each patient's specific motor deficits, can better support physical function compared with usual care physiotherapy in people with ALS. The individualized program is guided by diagnostic assessments using a robotic leg press system, which helps identify strengths and weaknesses in muscle function and movement control. Participants will receive either individualized physiotherapy or standard physiotherapy and will be followed for 12 months. The aim of the study is to improve physiotherapy strategies for people with ALS in a safe and patient-centered manner.
Eligibility Criteria
Inclusion Criteria: * diagnosis of clinically probable, probable laboratory-supported, or definite ALS (revised El Escorial criteria) or upper motor neuron only (OPM classification \[onset, propagation, motoneuron involvement\]) * age ≥18 years; ability to understand study information and provide written informed consent * Willingness and ability to perform individualized exercise according to the study protocol (approximately three to five sessions of 30 minutes per week) for the duration of the intervention period * Individuals of all sexes and gender identities are eligible for inclusion Exclusion Criteria: * pregnancy, tracheostomy, continuous assisted ventilation, or other significant non-ALS pulmonary disease * other neurodegenerative or neuromuscular conditions that may confound assessments * concomitant life-threatening disease or impairment interfering with functional assessment
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07341984 clinical trial?
This trial is open to participants of all sexes, studying Amyotrophic Lateral Sclerosis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07341984 currently recruiting?
Yes, NCT07341984 is actively recruiting participants. Contact the research team at charlotte.vogt@h-och.ch for enrollment information.
Where is the NCT07341984 trial being conducted?
This trial is being conducted at Sankt Gallen, Switzerland.
Who is sponsoring the NCT07341984 clinical trial?
NCT07341984 is sponsored by Charlotte Vogt. The trial plans to enroll 38 participants.
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