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Recruiting NCT00024804

NCT00024804 A Natural History Study of Bone and Mineral Disorders

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Clinical Trial Summary
NCT ID NCT00024804
Status Recruiting
Phase
Sponsor National Institute of Dental and Craniofacial Research (NIDCR)
Condition Tumor Induced Osteomalcia
Study Type OBSERVATIONAL
Enrollment 1,000 participants
Start Date 2001-11-19
Primary Completion

Eligibility & Interventions

Sex All sexes
Min Age 1 Day
Max Age 100 Years
Study Type OBSERVATIONAL

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 1,000 participants in total. It began in 2001-11-19.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study has four objectives: 1) to provide investigators the opportunity to study bone specimens from patients with various skeletal diseases; 2) to treat patients with skeletal diseases at the NIH; 3) to expose NIH trainees to certain skeletal diseases; and 4) to gain more knowledge about skeletal diseases and stimulate further study of bone biology. Anyone with a disease that affects the skeleton may be eligible for this study. All evaluations, tests, procedures and treatments given study participants are used in the standard care of skeletal diseases. No experimental evaluations or treatments are offered. Patient evaluations include a medical history, review of medical records and routine physical examination. Based on the findings, other procedures may be recommended, including blood tests, urine tests, and imaging tests, such as X-rays, bone densitometry, bone scan, computed tomography (CT) and magnetic resonance imaging (MRI). Bone specimens from participants will be collected for research use. Specimens will be obtained from bone removed during a patient s planned surgical procedure performed for medical care, or patients may be requested to have a bone biopsy removal of a small piece of bone tissue as part of the patient evaluation procedure. ...

Eligibility Criteria

* INCLUSION CRITERIA: The study population will include participants with known or suspected bone disease and/or with a known or suspected disorder of mineral metabolism. To be eligible to participate in this study, an individual must meet all of the following criteria: 1. Age 1 day of life or older 2. Have a known or suspected bone disease, as demonstrated by any one of the following: a fracture, or abnormal bone findings on x-ray, CT scan, MRI, or bone densitometry, and/or a medical or family history consistent with or suggestive of a bone disease. 3. Have a known or suspected disorder of mineral metabolism, as demonstrated by any one of the following: laboratory measurement above or below the reference values for either blood or urine calcium, phosphorus, magnesium, parathyroid hormone or vitamin D, or other measures of mineral metabolism, and/or a medical or family history consistent with or suggestive of a disorder of mineral metabolism. EXCLUSION CRITERIA: 1\. Participants unwilling or unable to abide by the procedures of the protocol.

Contact & Investigator

Central Contact

Elizabeth A Ferguson

✉ elizabeth.ferguson@nih.gov

📞 (240) 687-3029

Principal Investigator

Kelly B Roszko, M.D.

PRINCIPAL INVESTIGATOR

National Institute of Dental and Craniofacial Research (NIDCR)

Frequently Asked Questions

Who can join the NCT00024804 clinical trial?

This trial is open to participants of all sexes, aged 1 Day or older, up to 100 Years, studying Tumor Induced Osteomalcia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT00024804 currently recruiting?

Yes, NCT00024804 is actively recruiting participants. Contact the research team at elizabeth.ferguson@nih.gov for enrollment information.

Where is the NCT00024804 trial being conducted?

This trial is being conducted at Bethesda, United States.

Who is sponsoring the NCT00024804 clinical trial?

NCT00024804 is sponsored by National Institute of Dental and Craniofacial Research (NIDCR). The principal investigator is Kelly B Roszko, M.D. at National Institute of Dental and Craniofacial Research (NIDCR). The trial plans to enroll 1,000 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology