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Recruiting NCT06559475

A Multicenter, Randomized Controlled Clinical Investigation to Evaluate the Safety and Effectiveness of the Super-Bore 8/7F Aspiration Catheters in the Treatment of Acute Intracranial Large Vessel Occlusion

Trial Parameters

Condition Acute Ischemic Stroke
Sponsor The First Affiliated Hospital of University of Science and Technology of China
Study Type INTERVENTIONAL
Phase N/A
Enrollment 360
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2024-12-16
Completion 2025-12-01
Interventions
Super-Bore Thrombosis Aspiration Catheter treatment groupConventional thrombectomy device treatment group

Brief Summary

To Evaluate the Safety and Efficacy of the Super-Bore 8/7F Thrombosis Aspiration Catheter in the Treatment of Acute Intracranial Large Vessel Occlusion.

Eligibility Criteria

Inclusion Criteria: 1. Aged 18 years or older; 2. Clinical presentation consistent with acute ischemic stroke (AIS); 3. Able to receive mechanical thrombectomy within 24 hours of onset; 4. Pre-morbid mRS score of 0 or 1; 5. Baseline NIHSS score of 6 or greater; 6. Complete or near-complete occlusion (eTICI 0-1) of the intracranial segment of the internal carotid artery (ICA), the M1 segment of the middle cerebral artery (MCA), or the basilar artery (with or without involvement of the intracranial vertebral artery) confirmed by angiography who can undergo intravascular thrombectomy; 7. Vessel diameter ≥2.2 mm at the occlusion site; 8. ASPECTS or PC-ASPECTS score of 6-10 on NCCT, CTA-source imaging, or DWI-MRI; 9. Written informed consent obtained from the patient or the patient's qualified representative. Exclusion Criteria: 1. Pregnant or lactating women; 2. Severe allergic reactions to contrast agents; 3. Current participation in other clinical studies; 4. Known hereditary or acquired

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