NCT07548567 A Long Axis Approach to the Femoral Artery Block (FAB) for Managing Tourniquet Pain and Hypertension in Below-the-Knee Fracture Surgery
| NCT ID | NCT07548567 |
| Status | Recruiting |
| Phase | — |
| Sponsor | National and Kapodistrian University of Athens |
| Condition | Tourniquet Hypertension |
| Study Type | INTERVENTIONAL |
| Enrollment | 84 participants |
| Start Date | 2026-06-03 |
| Primary Completion | 2027-10 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 84 participants in total. It began in 2026-06-03 with a primary completion date of 2027-10.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This is a prospective, randomized, double-blind controlled trial evaluating an ultrasound-guided femoral artery block (FAB) using a long-axis in-plane approach compared with a short-axis approach and a control group. The study will include adult patients (ASA I-III) undergoing below-the-knee fracture surgery with tourniquet application. All patients will receive standardized anesthesia including sciatic nerve block and total intravenous anesthesia. Participants will be randomized into three groups: short-axis FAB, long-axis FAB, or control (saline injection). The primary aim is to assess the effectiveness of the long-axis FAB in reducing tourniquet-induced hypertension. Secondary outcomes include hemodynamic stability, analgesic requirements, pain scores, block characteristics, and procedural performance metrics.
Eligibility Criteria
Inclusion Criteria: * Age \>18 years * Physical status ASA I-III * Fluent in Greek or English * Scheduled surgery: below-knee fractures * Tourniquet duration ≥45 minutes Exclusion Criteria: * Refusal to participate * Local inflammation at block site * Known allergy to study drugs * Morbid obesity (BMI \>40) * Communication inability * Systemic neurological disease affecting peripheral nerves * Chronic pain therapy * Diabetic neuropathy * Uncontrolled hypertension
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07548567 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Tourniquet Hypertension. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07548567 currently recruiting?
Yes, NCT07548567 is actively recruiting participants. Contact the research team at banasiou_labrini@yahoo.com for enrollment information.
Where is the NCT07548567 trial being conducted?
This trial is being conducted at Athens, Greece.
Who is sponsoring the NCT07548567 clinical trial?
NCT07548567 is sponsored by National and Kapodistrian University of Athens. The trial plans to enroll 84 participants.