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Recruiting NCT06270927

A Feasibility Study for Randomization of Code Stroke Imaging Strategies

Trial Parameters

Condition Brain Ischemia
Sponsor University of Texas at Austin
Study Type OBSERVATIONAL
Phase N/A
Enrollment 600
Sex ALL
Min Age 18 Years
Max Age 120 Years
Start Date 2023-10-23
Completion 2025-03-30
Interventions
MRICT

Brief Summary

The purpose of this study is to test feasibility of a comparative effectiveness framework for acute stroke imaging using prospective electronic health data. This is a prospective, cohort feasibility study of patients presenting to the Emergency Department with suspected acute ischemic stroke. The clinical stroke team will not be blinded to the imaging modality given the nature and purpose of the interventions/imaging. Knowledge of the imaging modality used and the knowledge gained from the resulting data will need to be considered for treatment decisions. Blinding will be maintained for data abstraction and analyses. Analysis will be on an "intent-to-scan" basis and all qualifying patients will be included in their assigned cohort.

Eligibility Criteria

Inclusion Criteria: * Age ≥ 18 years * Time last known well to presentation ≤ 24 hours * Code-stroke (suspected treatable ischemic stroke) called prior to or upon arrival to Emergency Department * Presenting to Emergency Department for first time during study period Exclusion Criteria: * Transfer patients * Contraindication for brain perfusion scan * Prior inclusion in study

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