6-Month Trial of Chinese Herbal Treatments for Hair Loss and Gray Hair
Trial Parameters
Brief Summary
This will be a 6-month randomized, double-blind, placebo-controlled trial. A total of 152 participants with hair loss, including some with gray hair, will be enrolled and randomly assigned to four groups. Each group will receive a combination of oral capsules and hair tonic, to be used as directed for 24 weeks. Participants will attend three in-person visits, during which assessments-including hair-related tests and photographs-will be conducted to evaluate hair count and density. Additionally, 10 participants with gray hair from each group will undergo extra assessments focused on changes in hair color. All relevant clinical data will be systematically collected and recorded for statistical analysis.
Eligibility Criteria
Inclusion Criteria: 1. Participants must sign the informed consent form prior to enrollment and fully understand the study's purpose, procedures, and potential adverse events. 2. Adults aged 18 to 60 years, both male and female; each group must include no less than 50% female participants. 3. Hair length must be greater than 5 cm. 4. Women must meet the Savin scale classification between grades 1-3 to II. 5. Men must meet the Norwood-Hamilton classification between stages II and VI. 6. At least 10 participants in each group must have gray hair, with a minimum of 5 gray hairs within a 1 cm × 4 cm area of the scalp. 7. Participants must not have undergone any special hair treatments-such as dyeing, perming, or styling-within the past two months. Exclusion Criteria: 1. Pregnant or breastfeeding women, or individuals planning to conceive in the near future. 2. Individuals with medical conditions causing hair loss, such as refractory alopecia areata, inflammatory scarring alopecia, or psori