ClinicalMetric / Countries / United States / prostate cancer
← 🇺🇸 United States Trials
🇺🇸 United States Country × Condition

prostate cancer Clinical Trials in United States

Active clinical trials for prostate cancer with research sites in United States. All data sourced live from ClinicalTrials.gov — updated daily.

Active Trials: 47 // Recruiting: 47 Phases: Phase 1, Phase 2 // Updated: Daily
Total Trials
47
Recruiting Now
47
Country
🇺🇸 United States

Active Trials in United States (47)

NCT04706663
Recruiting

Precision-Based Genomics in Prostate Cancer

Enrollment
2,000 pts
Country
🇺🇸 United States
National Cancer Institute (NCI)
View Trial →
NCT05787587 Phase 1
Recruiting

A Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors

Enrollment
216 pts
Country
🇺🇸 United States
IDEAYA Biosciences
View Trial →
NCT04700332 Phase 2
Recruiting

PyL in Patients With High Risk and Biochemically Recurrent Prostate Cancer

Enrollment
184 pts
Country
🇺🇸 United States
Hoag Memorial Hospital Presbyterian
View Trial →
NCT00923221
Recruiting

Collection of Blood From Patients With Prostate Cancer

Enrollment
1,000 pts
Country
🇺🇸 United States
National Cancer Institute (NCI)
View Trial →
NCT06402357 Phase 2
Recruiting

High Intensity Focused Ultrasound in Prostate Cancer

Enrollment
25 pts
Country
🇺🇸 United States
University of Florida
View Trial →
NCT06817668
Recruiting

Evaluating Tolerability of ePUHRT With Brachytherapy Boost

Enrollment
31 pts
Country
🇺🇸 United States
Indiana University
View Trial →
NCT06237179 Phase 1, Phase 2
Recruiting

Behavioral Exercise Training to Reduce Cardiovascular Disease Risk

Enrollment
60 pts
Country
🇺🇸 United States
Virginia Commonwealth University
View Trial →
NCT06780670 Phase 2, Phase 3
Recruiting

Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy

Enrollment
443 pts
Country
🇺🇸 United States
Novartis Pharmaceuticals
View Trial →
NCT06395753 Phase 2
Recruiting

A Dose Finding Study of Debio 4228 in Participants With Advanced Prostate Cancer

Enrollment
66 pts
Country
🇺🇸 United States
Debiopharm International SA
View Trial →
NCT06202820
Recruiting

CV CARE: CardioVascular Care in PC Patients

Enrollment
180 pts
Country
🇺🇸 United States
Dana-Farber Cancer Institute
View Trial →
NCT00969111
Recruiting

Postoperative or Salvage Radiotherapy (RT) for Node Negative Prostate Cancer Following Radical Prostatectomy

Enrollment
70 pts
Country
🇺🇸 United States
Proton Collaborative Group
View Trial →
NCT07084779
Recruiting

Investigation of Impact of AI on Prostate Cancer Workflow

Enrollment
150 pts
Country
🇺🇸 United States
Case Comprehensive Cancer Center
View Trial →
NCT02064673 Phase 3
Recruiting

Adjuvant Curcumin to Assess Recurrence Free Survival in Patients Who Have Had a Radical Prostatectomy

Enrollment
608 pts
Country
🇺🇸 United States
yair lotan
View Trial →
NCT06925737 Phase 3
Recruiting

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

Enrollment
1,440 pts
Country
🇺🇸 United States
Merck Sharp & Dohme LLC
View Trial →
NCT05803941 Phase 4
Recruiting

Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer

Enrollment
700 pts
Country
🇺🇸 United States
Novartis Pharmaceuticals
View Trial →
NCT05958082
Recruiting

Utilization of Educational Interventions in Completion of Genetic Testing in Black Patients With High-Risk Prostate Cancer

Enrollment
50 pts
Country
🇺🇸 United States
Henry Ford Health System
View Trial →
NCT03424850 Phase 1, Phase 2
Recruiting

Safety and Efficacy of 21 Gy, 23 Gy and 25 Gy for High Dose Rate (HDR) Prostate Brachytherapy

Enrollment
36 pts
Country
🇺🇸 United States
Washington University School of Med...
View Trial →
NCT06395519 Phase 1, Phase 2
Recruiting

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

Enrollment
120 pts
Country
🇺🇸 United States
858 Therapeutics, Inc.
View Trial →
NCT01834001
Recruiting

Imaging Studies to Check the Local Response of Prostate Cancer to Radiation Therapy

Enrollment
300 pts
Country
🇺🇸 United States
National Cancer Institute (NCI)
View Trial →
NCT06398639
Recruiting

Polygenic Risk Stratification Combined With mpMRI to Identify Clinically Relevant Prostate Cancer

Enrollment
1,500 pts
Country
🇺🇸 United States
Adam S. Kibel, MD
View Trial →
NCT05435495
Recruiting

Mechanisms of Resistance to PSMA Radioligand Therapy

Enrollment
125 pts
Country
🇺🇸 United States
University of California, San Franc...
View Trial →
NCT05558241
Recruiting

Micro-UltraSound In Cancer - Active Surveillance

Enrollment
210 pts
Country
🇺🇸 United States
University of Alberta
View Trial →
NCT06384222 Phase 2
Recruiting

Hyperpolarized (HP) 13C Pyruvate Magnetic Resonance Imaging (MRI) for Response Monitoring to Neoadjuvant Abiraterone

Enrollment
32 pts
Country
🇺🇸 United States
Ivan de Kouchkovsky, MD
View Trial →
NCT04396808
Recruiting

Genomics in Michigan to AdJust Outcomes in Prostate canceR (G-MAJOR) for Men With Newly Diagnosed Favorable Risk Prostate Cancer

Enrollment
900 pts
Country
🇺🇸 United States
University of Michigan Rogel Cancer...
View Trial →
NCT05616650 Phase 2
Recruiting

Focal Therapy With Stereotactic Body Radiation Therapy (SBRT) for Patients With a Single Prostate Tumor

Enrollment
42 pts
Country
🇺🇸 United States
National Cancer Institute (NCI)
View Trial →
NCT07231159
Recruiting

Building on Trust: Navigating Preventive Lung, Breast, and Prostate Cancer Screenings at Community Resource Spots

Enrollment
200 pts
Country
🇺🇸 United States
AdventHealth
View Trial →
NCT05899361
Recruiting

A Novel Imaging Protocol in Use to Identify Lymph Nodes and Organs of Interest

Enrollment
10 pts
Country
🇺🇸 United States
Dana-Farber Cancer Institute
View Trial →
NCT06096870 Phase 2
Recruiting

Enzalutamide and PDS01ADC in PET Positive Recurrent Prostate Cancer (pprPC) Without Testosterone Lowering Therapy

Enrollment
65 pts
Country
🇺🇸 United States
National Cancer Institute (NCI)
View Trial →
NCT05879913
Recruiting

ASCVD Management Using CCTA in Prostate Cancer Patients on ADT

Enrollment
100 pts
Country
🇺🇸 United States
Indiana University
View Trial →
NCT06397703 Phase 2
Recruiting

ADT and SBRT vs SBRT Alone for Unfavorable Intermediate Risk Prostate Cancer

Enrollment
392 pts
Country
🇺🇸 United States
NYU Langone Health
View Trial →
NCT06440005 Phase 1
Recruiting

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

Enrollment
80 pts
Country
🇺🇸 United States
Angiex, Inc.
View Trial →
NCT07050433
Recruiting

COMPASS Study for Metastatic Castration-resistant Prostate Cancer

Enrollment
48 pts
Country
🇺🇸 United States
Duke University
View Trial →
NCT03802851
Recruiting

HoLEP Prior to Radiation Therapy for Patients With LUTS/Retention and Concurrent Prostate Cancer

Enrollment
30 pts
Country
🇺🇸 United States
University of Kansas Medical Center
View Trial →
NCT03127631
Recruiting

A RAndomizeD Intervention for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients

Enrollment
6,000 pts
Country
🇺🇸 United States
McMaster University
View Trial →
NCT05766371 Phase 2
Recruiting

Pembrolizumab Plus 177Lu-PSMA-617 in Patients With Castration Resistant Prostate Cancer

Enrollment
48 pts
Country
🇺🇸 United States
University of California, San Franc...
View Trial →
NCT05478694
Recruiting

Outcomes of Focal Ablation for Prostate Cancer

Enrollment
225 pts
Country
🇺🇸 United States
University of Texas Southwestern Me...
View Trial →
NCT06171269
Recruiting

Using MRI to Identify Areas to Receive Lower Doses of Radiation Treatment in Men With Prostate Cancerdose Mapping to Preserve Quality of Life

Enrollment
60 pts
Country
🇺🇸 United States
University of Chicago
View Trial →
NCT07028853 Phase 3
Recruiting

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

Enrollment
1,000 pts
Country
🇺🇸 United States
Pfizer
View Trial →
NCT02016248
Recruiting

SBRT Boost for Unfavorable Prostate Cancer'

Enrollment
150 pts
Country
🇺🇸 United States
MemorialCare Health System
View Trial →
NCT04887935 Phase 1
Recruiting

Neoadjuvant SGLT2 Inhibition in Localized Prostate Cancer

Enrollment
24 pts
Country
🇺🇸 United States
Washington University School of Med...
View Trial →
NCT05384535
Recruiting

Utility of Biparametric MRI (Magnetic Resonance Imaging) as a Screening Tool for Prostate Cancer in a High-Risk Cohort

Enrollment
100 pts
Country
🇺🇸 United States
Northwell Health
View Trial →
NCT04585750 Phase 1, Phase 2
Recruiting

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Enrollment
300 pts
Country
🇺🇸 United States
PMV Pharmaceuticals, Inc
View Trial →
NCT05381103 Phase 2, Phase 3
Recruiting

PSMA-PET to Guide Prostatectomy

Enrollment
288 pts
Country
🇺🇸 United States
Five Eleven Pharma, Inc.
View Trial →
NCT06059118 Phase 2
Recruiting

Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer

Enrollment
50 pts
Country
🇺🇸 United States
Sidney Kimmel Comprehensive Cancer ...
View Trial →
NCT03784924
Recruiting

EDRN Prostate MRI Biomarker Study

Enrollment
950 pts
Country
🇺🇸 United States
University of Michigan
View Trial →
NCT07042243
Recruiting

The Florida ASCENT Study

Enrollment
100 pts
Country
🇺🇸 United States
University of Florida
View Trial →
NCT05864196 Phase 1
Recruiting

Two Fraction Prostate SBRT With DIL SIB

Enrollment
80 pts
Country
🇺🇸 United States
NYU Langone Health
View Trial →

Frequently Asked Questions

How many prostate cancer clinical trials are active in United States?
There are currently 47 active clinical trials for prostate cancer with sites in United States, of which 47 are actively recruiting patients.
How can I join a prostate cancer clinical trial in United States?
To join a prostate cancer clinical trial in United States, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in United States directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.
What phases are prostate cancer trials in United States?
Active prostate cancer trials in United States span Phase 1, Phase 2, Phase 1, Phase 2, Phase 2, Phase 3, Phase 3, Phase 4. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.
Browse More
All United States Trials → Global prostate cancer Trials → All Countries → All Trials →