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ovarian cancer Clinical Trials in United States

Active clinical trials for ovarian cancer with research sites in United States. All data sourced live from ClinicalTrials.gov — updated daily.

Active Trials: 36 // Recruiting: 36 Phases: EARLY_Phase 1, Phase 1 // Updated: Daily
Total Trials
36
Recruiting Now
36
Country
🇺🇸 United States

Active Trials in United States (36)

NCT05080946 EARLY_Phase 1
Recruiting

Using Aspirin to Improve Immunological Features of Ovarian Tumors

Enrollment
100 pts
Country
🇺🇸 United States
H. Lee Moffitt Cancer Center and Re...
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NCT06710548
Recruiting

REVITALIZE: RCT to Reduce Fatigue in Adults With Ovarian Cancer on PARP Inhibitors

Enrollment
240 pts
Country
🇺🇸 United States
Dana-Farber Cancer Institute
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NCT00005095
Recruiting

Specimen and Data Study for Ovarian Cancer Early Detection and Prevention

Enrollment
6,000 pts
Country
🇺🇸 United States
Northwestern University
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NCT05366881
Recruiting

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

Enrollment
7,000 pts
Country
🇺🇸 United States
Adela, Inc
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NCT04038619 Phase 1
Recruiting

Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients

Enrollment
40 pts
Country
🇺🇸 United States
M.D. Anderson Cancer Center
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NCT07211659 Phase 1
Recruiting

Trial of THEO-260 (Administered Via Intraperitoneal Route) in Ovarian Cancer Patients

Enrollment
18 pts
Country
🇺🇸 United States
Theolytics Limited
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NCT02830724 Phase 1, Phase 2
Recruiting

Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers

Enrollment
124 pts
Country
🇺🇸 United States
National Cancer Institute (NCI)
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NCT06036810
Recruiting

Spanish Decision Tool for Ovarian Cancer Maintenance Therapy

Enrollment
70 pts
Country
🇺🇸 United States
M.D. Anderson Cancer Center
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NCT07186296
Recruiting

EXoPERT EMERALD Clinical Study

Enrollment
1,400 pts
Country
🇺🇸 United States
EXoPERT
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NCT06787612 Phase 2
Recruiting

Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

Enrollment
220 pts
Country
🇺🇸 United States
Regeneron Pharmaceuticals
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NCT05086692 Phase 1, Phase 2
Recruiting

A Beta-only IL-2 ImmunoTherapY Study

Enrollment
115 pts
Country
🇺🇸 United States
Medicenna Therapeutics, Inc.
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NCT06504147 Phase 2
Recruiting

A Study of Radspherin® in Patients With Primary Advanced Epithelial Cancer, With Peritoneal Metastasis That Are Homologous Recombination Proficient Scheduled to Undergo Neoadjuvant Chemotherapy and Interval Debulking Surgery

Enrollment
114 pts
Country
🇺🇸 United States
Oncoinvent Solutions AS
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NCT04752826 Phase 1, Phase 2
Recruiting

BI-1808 as a Single Agent and With Pembrolizumab (KEYTRUDA® ) in Treatment of Advanced Malignancies(Keynote-D20)

Enrollment
176 pts
Country
🇺🇸 United States
BioInvent International AB
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NCT06646627 Phase 1
Recruiting

Clinical Trial of Autologous B7-H3 CAR T Cells in Reoccurent Platinum-resistant Ovarian Tumors

Enrollment
48 pts
Country
🇺🇸 United States
Stanford University
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NCT06366490 Phase 1
Recruiting

Safety and Immunogenicity of Innocell Autologous Cellular Immunotherapy for Recurrent Epithelial Ovarian Cancer

Enrollment
8 pts
Country
🇺🇸 United States
PhotonPharma, Inc.
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NCT07216105 Phase 1
Recruiting

FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors

Enrollment
113 pts
Country
🇺🇸 United States
Fate Therapeutics
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NCT05735080 Phase 1, Phase 2
Recruiting

Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer

Enrollment
150 pts
Country
🇺🇸 United States
Incyclix Bio
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NCT05377996 Phase 1, Phase 2
Recruiting

A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors

Enrollment
360 pts
Country
🇺🇸 United States
Day One Biopharmaceuticals, Inc.
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NCT07524322 Phase 1
Recruiting

Study of RGT-490 in Patients With PIK3CA-Mutated Advanced Solid Tumors

Enrollment
63 pts
Country
🇺🇸 United States
Regor Pharmaceuticals Inc.
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NCT07070726
Recruiting

UNTOLD Ovarian Cancer Unmet Needs Survey

Enrollment
2,000 pts
Country
🇺🇸 United States
Masonic Cancer Center, University o...
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NCT07182149 Phase 1
Recruiting

A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

Enrollment
150 pts
Country
🇺🇸 United States
Normunity AccelCo, Inc.
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NCT05739981 Phase 1, Phase 2
Recruiting

Phase II IMNN-001 (Also Known as GEN-1) on SLL With BEV and NACT, Newly Diagnosed Advanced Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Enrollment
30 pts
Country
🇺🇸 United States
Imunon
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NCT06545604
Recruiting

Comprehensive Yoga Therapy Based Lifestyle Prehabilitation Program for Women With Ovarian Cancer

Enrollment
40 pts
Country
🇺🇸 United States
M.D. Anderson Cancer Center
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NCT04520139 Phase 1, Phase 2
Recruiting

Effect of NAC on Preventing Chemo-Related Cognitive Impairments in Ovarian Ca Pts Treated W/ PBT

Enrollment
102 pts
Country
🇺🇸 United States
University of California, Irvine
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NCT04606914 Phase 2
Recruiting

Study of Carboplatin and Mirvetuximab Soravtansine in First-Line Treatment of Patients Receiving Neoadjuvant Chemotherapy With Advanced-Stage Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Enrollment
70 pts
Country
🇺🇸 United States
University of Alabama at Birmingham
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NCT04585750 Phase 1, Phase 2
Recruiting

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Enrollment
300 pts
Country
🇺🇸 United States
PMV Pharmaceuticals, Inc
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NCT07225270 Phase 3
Recruiting

Study to Assess the Efficacy and Safety of Rina-S Plus Standard of Care Compared to Standard of Care for Maintenance Treatment of Participants With Recurrent Platinum-sensitive Ovarian Cancer After Second-line (2L) Platinum-based Doublet Chemotherapy

Enrollment
544 pts
Country
🇺🇸 United States
Genmab
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NCT07125209
Recruiting

Cognitive Impact of Neoadjuvant Chemotherapy for Ovarian Cancer

Enrollment
18 pts
Country
🇺🇸 United States
University of Wisconsin, Madison
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NCT05983276 Phase 2
Recruiting

Decitabine and Selinexor in Combination to Reverse Drug Resistance With Standard Chemotherapy in Ovarian Cancer

Enrollment
40 pts
Country
🇺🇸 United States
Loyola University
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NCT04294927
Recruiting

TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention

Enrollment
3,000 pts
Country
🇺🇸 United States
University Medical Center Nijmegen
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NCT06943521 Phase 1, Phase 2
Recruiting

A Study of MT-4561 in Patients With Various Advanced Solid Tumors

Enrollment
27 pts
Country
🇺🇸 United States
Tanabe Pharma America, Inc.
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NCT06774963 Phase 1
Recruiting

A Phase 1 Study of LNCB74 in Advanced Solid Tumors

Enrollment
145 pts
Country
🇺🇸 United States
NextCure, Inc.
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NCT06677190 Phase 2
Recruiting

Belzutifan in Recurrent Clear Cell Carcinoma of Gynecologic Origin

Enrollment
32 pts
Country
🇺🇸 United States
Dana-Farber Cancer Institute
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NCT06695845 Phase 2
Recruiting

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

Enrollment
200 pts
Country
🇺🇸 United States
Jazz Pharmaceuticals
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NCT06305299 Phase 1
Recruiting

Autologous CAR-T Cells Targeting B7H3 in Ovarian Cancer iC9-CAR.B7-H3 T Cells

Enrollment
27 pts
Country
🇺🇸 United States
UNC Lineberger Comprehensive Cancer...
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NCT07030907 Phase 1
Recruiting

A Study to Evaluate the Safety and Efficacy of OPB-101 in Platinum-resistant Ovarian Cancer

Enrollment
30 pts
Country
🇺🇸 United States
Outpace Bio, Inc.
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Frequently Asked Questions

How many ovarian cancer clinical trials are active in United States?
There are currently 36 active clinical trials for ovarian cancer with sites in United States, of which 36 are actively recruiting patients.
How can I join a ovarian cancer clinical trial in United States?
To join a ovarian cancer clinical trial in United States, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in United States directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.
What phases are ovarian cancer trials in United States?
Active ovarian cancer trials in United States span EARLY_Phase 1, Phase 1, Phase 1, Phase 2, Phase 2, Phase 3. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.
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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology