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ovarian cancer Clinical Trials in United States

Active clinical trials for ovarian cancer with research sites in United States. All data sourced live from ClinicalTrials.gov — updated daily.

Active Trials: 25 // Recruiting: 25 Phases: Phase 2, Phase 1 // Updated: Daily
Total Trials
25
Recruiting Now
25
Country
🇺🇸 United States

Active Trials in United States (25)

NCT06906341 Phase 2
Recruiting

Relacorilant in Combination With Different Treatment Regimens in Patients With Gynecological Cancers

Enrollment
270 pts
Country
🇺🇸 United States
Corcept Therapeutics
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NCT05103683 Phase 1
Recruiting

First in Human Study of TORL-1-23 in Participants With Advanced Cancer

Enrollment
90 pts
Country
🇺🇸 United States
TORL Biotherapeutics, LLC
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NCT05071937 Phase 2
Recruiting

ZEN003694 Combined With Talazoparib in Patients With Recurrent Ovarian Cancer

Enrollment
33 pts
Country
🇺🇸 United States
Alexander B Olawaiye, MD
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NCT05739981 Phase 1, Phase 2
Recruiting

Phase II IMNN-001 (Also Known as GEN-1) on SLL With BEV and NACT, Newly Diagnosed Advanced Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Enrollment
30 pts
Country
🇺🇸 United States
Imunon
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NCT06305299 Phase 1
Recruiting

Autologous CAR-T Cells Targeting B7H3 in Ovarian Cancer iC9-CAR.B7-H3 T Cells

Enrollment
27 pts
Country
🇺🇸 United States
UNC Lineberger Comprehensive Cancer...
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NCT05877599 Phase 1
Recruiting

A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

Enrollment
45 pts
Country
🇺🇸 United States
AstraZeneca
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NCT04520139 Phase 1, Phase 2
Recruiting

Effect of NAC on Preventing Chemo-Related Cognitive Impairments in Ovarian Ca Pts Treated W/ PBT

Enrollment
102 pts
Country
🇺🇸 United States
University of California, Irvine
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NCT05983432 Phase 1
Recruiting

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

Enrollment
470 pts
Country
🇺🇸 United States
SystImmune Inc.
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NCT05113368 Phase 2
Recruiting

Regorafenib Combined With Fulvestrant in Recurrent Low-Grade Serous Ovarian Cancer

Enrollment
31 pts
Country
🇺🇸 United States
Sarah K. Lynam MD
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NCT06242470 Phase 1
Recruiting

A Study of MGC026 in Participants With Advanced Solid Tumors

Enrollment
250 pts
Country
🇺🇸 United States
MacroGenics
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NCT07564141 Phase 3
Recruiting

Study to Assess the Efficacy and Safety of Rina-S With or Without Bevacizumab Compared to Investigator's Choice of Platinum-based Chemotherapy With or Without Bevacizumab as Second-line Treatment in Participants With Recurrent Platinum-sensitive Ovarian Cancer

Enrollment
688 pts
Country
🇺🇸 United States
Genmab
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NCT05377996 Phase 1, Phase 2
Recruiting

A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors

Enrollment
360 pts
Country
🇺🇸 United States
Day One Biopharmaceuticals, Inc.
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NCT05000294 Phase 1, Phase 2
Recruiting

Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types

Enrollment
29 pts
Country
🇺🇸 United States
University of Florida
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NCT04847063 Phase 1
Recruiting

Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies

Enrollment
60 pts
Country
🇺🇸 United States
National Cancer Institute (NCI)
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NCT07424547 Phase 1
Recruiting

Phase I Study of SYS6043 in Patients With Advanced/Metastatic Solid Tumors

Enrollment
386 pts
Country
🇺🇸 United States
Conjupro Biotherapeutics, Inc.
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NCT06840886 Phase 1
Recruiting

A Study of PHST001 in Advanced Solid Tumors

Enrollment
272 pts
Country
🇺🇸 United States
Pheast Therapeutics
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NCT06303505 Phase 1, Phase 2
Recruiting

FiH Study to Investigate Safety, PK and Efficacy of the NaPi2b ADC TUB-040 in Patients With PROC or r/r Adenocarcinoma NSCLC

Enrollment
250 pts
Country
🇺🇸 United States
Tubulis GmbH
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NCT06580002 Phase 2
Recruiting

Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial

Enrollment
75 pts
Country
🇺🇸 United States
University of California, Irvine
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NCT01034033
Recruiting

Genetic & Pathological Studies of BRCA1/BRCA2: Associated Tumors & Blood Samples

Enrollment
3,300 pts
Country
🇺🇸 United States
Stanford University
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NCT04606914 Phase 2
Recruiting

Study of Carboplatin and Mirvetuximab Soravtansine in First-Line Treatment of Patients Receiving Neoadjuvant Chemotherapy With Advanced-Stage Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Enrollment
70 pts
Country
🇺🇸 United States
University of Alabama at Birmingham
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NCT06910657 Phase 1
Recruiting

IDOV-Immune for Advanced Solid Tumors

Enrollment
78 pts
Country
🇺🇸 United States
ViroMissile, Inc.
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NCT06268665 Phase 2
Recruiting

Tart Cherry Juice as a Dietary Supplement for the Prevention of Paclitaxel-Induced Neuropathy

Enrollment
86 pts
Country
🇺🇸 United States
University of California, Davis
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NCT07524322 Phase 1
Recruiting

Study of RGT-490 in Patients With PIK3CA-Mutated Advanced Solid Tumors

Enrollment
63 pts
Country
🇺🇸 United States
Regor Pharmaceuticals Inc.
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NCT07216105 Phase 1
Recruiting

FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors

Enrollment
119 pts
Country
🇺🇸 United States
Fate Therapeutics
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NCT06695845 Phase 2
Recruiting

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

Enrollment
200 pts
Country
🇺🇸 United States
Jazz Pharmaceuticals
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Frequently Asked Questions

How many ovarian cancer clinical trials are active in United States?
There are currently 25 active clinical trials for ovarian cancer with sites in United States, of which 25 are actively recruiting patients.
How can I join a ovarian cancer clinical trial in United States?
To join a ovarian cancer clinical trial in United States, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in United States directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.
What phases are ovarian cancer trials in United States?
Active ovarian cancer trials in United States span Phase 2, Phase 1, Phase 1, Phase 2, Phase 3. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.
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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology