🇺🇸 United States Country × Condition
multiple myeloma Clinical Trials in United States
Active clinical trials for multiple myeloma with research sites in United States. All data sourced live from ClinicalTrials.gov — updated daily.
Active Trials: 23 // Recruiting: 23 Phases: Phase 1, Phase 2, Phase 1 // Updated: Daily
Total Trials
23
Recruiting Now
23
Country
🇺🇸 United States
Active Trials in United States (23)
NCT05372354 Phase 1, Phase 2
Recruiting
A Study to Evaluate Safety, Drug Levels and Effectiveness of CC-92480 (BMS-986348) in Combination With Other Treatments in Participants With Relapsed or Refractory Multiple Myeloma
Enrollment
260 pts
Country
🇺🇸 United States
Bristol-Myers Squibb
View Trial → NCT05366881
Recruiting
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
Enrollment
7,000 pts
Country
🇺🇸 United States
Adela, Inc
View Trial → NCT06623630 Phase 1
Recruiting
Lymphodepleting Total Body Irradiation (TBI) Plus Cyclophosphamide Prior to Ciltacabtagene Autoleucel (Carvykti; Cilta-cel) for Multiple Myeloma (MM) Patients With Impaired Renal Function
Enrollment
16 pts
Country
🇺🇸 United States
Washington University School of Med...
View Trial → NCT06107738 Phase 2
Recruiting
Iberdomide and Daratumumab as Maintenance Therapy After an Autologous Stem Cell Transplant for Multiple Myeloma
Enrollment
60 pts
Country
🇺🇸 United States
Barbara Ann Karmanos Cancer Institu...
View Trial → NCT03127761
Recruiting
Assessment of Allogeneic Hematopoietic Cell Transplantation in Medicare Beneficiaries With Multiple Myeloma
Enrollment
544 pts
Country
🇺🇸 United States
Center for International Blood and ...
View Trial → NCT06158841 Phase 3
Recruiting
Study Assessing Activity of Intravenous (IV) Etentamig Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple Myeloma
Enrollment
380 pts
Country
🇺🇸 United States
AbbVie
View Trial → NCT06338150
Recruiting
Precision Medicine Study
Enrollment
100 pts
Country
🇺🇸 United States
Icahn School of Medicine at Mount S...
View Trial → NCT06270888 Phase 1
Recruiting
Hypofractionation (Radiation) Trial for Multiple Myeloma
Enrollment
30 pts
Country
🇺🇸 United States
University of Chicago
View Trial → NCT04991103 Phase 2
Recruiting
Minimal Residual Disease Response-adapted Deferral of Transplant in Dysproteinemia (MILESTONE)
Enrollment
40 pts
Country
🇺🇸 United States
University of Alabama at Birmingham
View Trial → NCT06121843 Phase 1
Recruiting
A Study to Evaluate the Safety, Effectiveness and Tolerable Dose of Arlocabtagene Autoleucel (BMS-986393) in Novel Combinations in Participants With Relapsed and/or Refractory Multiple Myeloma
Enrollment
187 pts
Country
🇺🇸 United States
Juno Therapeutics, Inc., a Bristol-...
View Trial → NCT07101445 Phase 4
Recruiting
Evaluating Premedication Regimens (Methylprednisolone vs Dexamethasone-based) for the Prevention of Systemic and Injection Site Reactions to Motixafortide in Patients With Multiple Myeloma Undergoing Stem Cell Mobilization, PARADE Trial
Enrollment
94 pts
Country
🇺🇸 United States
Emory University
View Trial → NCT03375619
Recruiting
Long-term Follow-up Study of Patients Receiving CAR-T Cells
Enrollment
500 pts
Country
🇺🇸 United States
Medical College of Wisconsin
View Trial → NCT04483206 Phase 1
Recruiting
Personalized Autologous Transplant for Multiple Myeloma
Enrollment
90 pts
Country
🇺🇸 United States
Emory University
View Trial → NCT07284758 Phase 2
Recruiting
A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma
Enrollment
100 pts
Country
🇺🇸 United States
C4 Therapeutics, Inc.
View Trial → NCT06297226 Phase 2
Recruiting
Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma
Enrollment
230 pts
Country
🇺🇸 United States
Juno Therapeutics, Inc., a Bristol-...
View Trial → NCT05737732
Recruiting
The Ambient Light Multiple Myeloma Study
Enrollment
200 pts
Country
🇺🇸 United States
Icahn School of Medicine at Mount S...
View Trial → NCT06052826 Phase 2
Recruiting
Geriatric Assessment Guided Interventions to Accelerate Functional Recovery After CAR-T Therapy for Patients 60 Years and Older With B-cell Non-Hodgkin Lymphoma or Multiple Myeloma, GOCART Study
Enrollment
164 pts
Country
🇺🇸 United States
City of Hope Medical Center
View Trial → NCT07266441 Phase 2
Recruiting
A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma
Enrollment
157 pts
Country
🇺🇸 United States
Janssen Research & Development, LLC
View Trial → NCT05623020 Phase 3
Recruiting
A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant
Enrollment
1,116 pts
Country
🇺🇸 United States
Pfizer
View Trial → NCT05556928
Recruiting
Cancer and Aging Resilience Evaluation in Older Adults With Hematologic Malignancies: The CARE-Heme Registry
Enrollment
5,000 pts
Country
🇺🇸 United States
University of Alabama at Birmingham
View Trial → NCT07226609
Recruiting
A Dietary Study for People With Multiple Myeloma
Enrollment
220 pts
Country
🇺🇸 United States
Memorial Sloan Kettering Cancer Cen...
View Trial → NCT06536413 Phase 1, Phase 2
Recruiting
ATRA and Carfilzomib in Plasma Cell Myeloma Patients
Enrollment
42 pts
Country
🇺🇸 United States
The Methodist Hospital Research Ins...
View Trial → NCT06572605 Phase 1, Phase 2
Recruiting
External Beam Radiation Therapy in Combination With Talquetamab for the Treatment of Multiple Myeloma Patients With Extramedullary Disease
Enrollment
20 pts
Country
🇺🇸 United States
City of Hope Medical Center
View Trial → Frequently Asked Questions
How many multiple myeloma clinical trials are active in United States?
There are currently 23 active clinical trials for multiple myeloma with sites in United States, of which 23 are actively recruiting patients.
How can I join a multiple myeloma clinical trial in United States?
To join a multiple myeloma clinical trial in United States, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in United States directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.
What phases are multiple myeloma trials in United States?
Active multiple myeloma trials in United States span Phase 1, Phase 2, Phase 1, Phase 2, Phase 3, Phase 4. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: July 2026 · Data Methodology