🇺🇸 United States Country × Condition
mild cognitive impairment Clinical Trials in United States
Active clinical trials for mild cognitive impairment with research sites in United States. All data sourced live from ClinicalTrials.gov — updated daily.
Active Trials: 19 // Recruiting: 19 Phases: Phase 2, Phase 1 // Updated: Daily
Total Trials
19
Recruiting Now
19
Country
🇺🇸 United States
Active Trials in United States (19)
NCT04804241 Phase 2
Recruiting
Senicapoc in Alzheimer's Disease
Enrollment
55 pts
Country
🇺🇸 United States
University of California, Davis
View Trial → NCT05591027 Phase 1
Recruiting
Safety and Target Engagement of Centella Asiatica in Cognitive Impairment
Enrollment
48 pts
Country
🇺🇸 United States
Oregon Health and Science Universit...
View Trial → NCT06982261
Recruiting
Voice Technology-Based Self-Management Intervention
Enrollment
20 pts
Country
🇺🇸 United States
Emory University
View Trial → NCT06005038 Phase 1
Recruiting
CogT pSOPT Intervention Study
Enrollment
50 pts
Country
🇺🇸 United States
Stanford University
View Trial → NCT06102486
Recruiting
MCI Speech in Noise
Enrollment
70 pts
Country
🇺🇸 United States
Dartmouth-Hitchcock Medical Center
View Trial → NCT05396248
Recruiting
Improve New Learning and Memory in Individuals With Mild Cognitive Impairment
Enrollment
120 pts
Country
🇺🇸 United States
Kessler Foundation
View Trial → NCT04123314 EARLY_Phase 1
Recruiting
Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease
Enrollment
20 pts
Country
🇺🇸 United States
Johns Hopkins University
View Trial → NCT07012993 Phase 2
Recruiting
Ultralow Dose PET Imaging of 18F-Florbetapir, 18F-Flutemetamol
Enrollment
200 pts
Country
🇺🇸 United States
Akiva Mintz
View Trial → NCT04396873 Phase 1
Recruiting
PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease
Enrollment
184 pts
Country
🇺🇸 United States
National Institute of Mental Health...
View Trial → NCT06703541
Recruiting
ADRC Clinical Cohort (Alzheimer's Disease)
Enrollment
500 pts
Country
🇺🇸 United States
Duke University
View Trial → NCT04171323
Recruiting
The Active Mind Trial: An Adaptive Randomized Trial to Improve Function and Delay Dementia
Enrollment
1,305 pts
Country
🇺🇸 United States
University of Alabama at Birmingham
View Trial → NCT05655325
Recruiting
Accelerated Age-related Cognitive Decline: Impact of Exercise on Executive Function and Neuroplasticity
Enrollment
144 pts
Country
🇺🇸 United States
Columbia University
View Trial → NCT07169630 Phase 1
Recruiting
PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)
Enrollment
90 pts
Country
🇺🇸 United States
National Institute of Mental Health...
View Trial → NCT05968703
Recruiting
Combined STN and NBM Deep Brain Stimulation for Mild Cognitive Impairment in Parkinson's Disease
Enrollment
10 pts
Country
🇺🇸 United States
Helen M. Bronte-Stewart
View Trial → NCT03233646
Recruiting
Retinal Imaging in Neurodegenerative Disease
Enrollment
2,000 pts
Country
🇺🇸 United States
Duke University
View Trial → NCT07846566
Recruiting
Choose Myself (Before) Losing Myself
Enrollment
25 pts
Country
🇺🇸 United States
The Cleveland Clinic
View Trial → NCT05904132
Recruiting
Individual Closed-Loop Neuromodulation Therapy for Alzheimer's Disease
Enrollment
70 pts
Country
🇺🇸 United States
Massachusetts General Hospital
View Trial → NCT05948930
Recruiting
Working Memory and Physical Exercise Training in Patients With Mild Cognitive Impairment
Enrollment
90 pts
Country
🇺🇸 United States
University of Maryland, Baltimore
View Trial → NCT05795634
Recruiting
Cognitive Vulnerability to Stress in Individuals at Risk for Alzheimer's Disease
Enrollment
240 pts
Country
🇺🇸 United States
Johns Hopkins University
View Trial → Frequently Asked Questions
How many mild cognitive impairment clinical trials are active in United States?
There are currently 19 active clinical trials for mild cognitive impairment with sites in United States, of which 19 are actively recruiting patients.
How can I join a mild cognitive impairment clinical trial in United States?
To join a mild cognitive impairment clinical trial in United States, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in United States directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.
What phases are mild cognitive impairment trials in United States?
Active mild cognitive impairment trials in United States span Phase 2, Phase 1, EARLY_Phase 1. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology