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lung cancer Clinical Trials in United States

Active clinical trials for lung cancer with research sites in United States. All data sourced live from ClinicalTrials.gov — updated daily.

Active Trials: 22 // Recruiting: 22 Phases: Phase 2, Phase 1 // Updated: Daily
Total Trials
22
Recruiting Now
22
Country
🇺🇸 United States

Active Trials in United States (22)

NCT06199570
Recruiting

Support for Cancer Patients Awaiting News

Enrollment
60 pts
Country
🇺🇸 United States
Hackensack Meridian Health
View Trial →
NCT04115254
Recruiting

Stereotactic Magnetic Resonance Guided Radiation Therapy

Enrollment
397 pts
Country
🇺🇸 United States
Dana-Farber Cancer Institute
View Trial →
NCT03290534 Phase 2
Recruiting

Feasibility Study to Treat Lung Cancer With the Permanently Implantable LDR CivaSheet®

Enrollment
40 pts
Country
🇺🇸 United States
CivaTech Oncology
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NCT07572773
Recruiting

CHAMP Lung Cancer Screening Program

Enrollment
300 pts
Country
🇺🇸 United States
Jill Kolesar
View Trial →
NCT00898313
Recruiting

Molecular Predictors of Cancer in Patients at High Risk of Lung Cancer

Enrollment
4,000 pts
Country
🇺🇸 United States
Vanderbilt-Ingram Cancer Center
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NCT06432972
Recruiting

Accelerated Pulmonary Rehabilitation in the Preoperative Period

Enrollment
20 pts
Country
🇺🇸 United States
University of Vermont
View Trial →
NCT06538636
Recruiting

Prediction Augmented Screening Initiative

Enrollment
23,520 pts
Country
🇺🇸 United States
VA Office of Research and Developme...
View Trial →
NCT03563976
Recruiting

Multiparametric Image Analysis and Correlation With Outcomes in Lung Cancer Screening and Early Stage Lung Cancer

Enrollment
2,000 pts
Country
🇺🇸 United States
University of Texas Southwestern Me...
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NCT07685938 Phase 2
Recruiting

Pharmacologic Therapies to Mitigate Radiation- Associated Heart Disease

Enrollment
60 pts
Country
🇺🇸 United States
UNC Lineberger Comprehensive Cancer...
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NCT06577883
Recruiting

Next Generation Chest X-Ray Tomosynthesis for Screening of Lung Cancer

Enrollment
1,000 pts
Country
🇺🇸 United States
University of California, San Diego
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NCT05171478
Recruiting

Full-Field Optical Coherence Tomography (FFOCT) for Evaluation of Bronchoscopic Small Biopsy Specimens

Enrollment
20 pts
Country
🇺🇸 United States
Johns Hopkins University
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NCT07042243
Recruiting

The Florida ASCENT Study

Enrollment
100 pts
Country
🇺🇸 United States
University of Florida
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NCT04038619 Phase 1
Recruiting

Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients

Enrollment
40 pts
Country
🇺🇸 United States
M.D. Anderson Cancer Center
View Trial →
NCT04075305
Recruiting

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

Enrollment
8,000 pts
Country
🇺🇸 United States
UMC Utrecht
View Trial →
NCT07168629
Recruiting

A Community Health Intervention to Improve Lung Cancer Screening Uptake in Community Health Centers

Enrollment
120 pts
Country
🇺🇸 United States
Baystate Medical Center
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NCT00471978
Recruiting

DNA Analysis of Blood and Tissue From Patients With Lung Cancer

Enrollment
15,000 pts
Country
🇺🇸 United States
Massachusetts General Hospital
View Trial →
NCT07354919 Phase 2
Recruiting

Axelopran for Advanced Cancer in Patients Receiving Opioids

Enrollment
34 pts
Country
🇺🇸 United States
HealthPartners Institute
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NCT07460440
Recruiting

SPARC - Screening for Lung Cancer With Platelets Via an AI-enabled RNA-based Classifier

Enrollment
240 pts
Country
🇺🇸 United States
University of Utah
View Trial →
NCT06910956
Recruiting

Deep Learning Using Chest X-Rays to Identify High Risk Patients for Lung Cancer Screening CT

Enrollment
1,500 pts
Country
🇺🇸 United States
Massachusetts General Hospital
View Trial →
NCT03535545 Phase 1
Recruiting

Preliminary Evaluation of [68Ga]CBP8 in Healthy Individuals, Lung Cancer, and Idiopathic Pulmonary Fibrosis Patients

Enrollment
100 pts
Country
🇺🇸 United States
Massachusetts General Hospital
View Trial →
NCT05968898
Recruiting

Assessment of a Radiomics-based Computer-Aided Diagnosis Tool for Pulmonary nodulES

Enrollment
300 pts
Country
🇺🇸 United States
Abramson Cancer Center at Penn Medi...
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NCT05987644 Phase 1, Phase 2
Recruiting

Delayed or Upfront Brain RAdiotherapy in Treatment naïve Lung Cancer Patients With Asymptomatic or Minimally Symptomatic Brain Metastases and ALK rEarrangements

Enrollment
56 pts
Country
🇺🇸 United States
Joshua Palmer
View Trial →

Frequently Asked Questions

How many lung cancer clinical trials are active in United States?
There are currently 22 active clinical trials for lung cancer with sites in United States, of which 22 are actively recruiting patients.
How can I join a lung cancer clinical trial in United States?
To join a lung cancer clinical trial in United States, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in United States directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.
What phases are lung cancer trials in United States?
Active lung cancer trials in United States span Phase 2, Phase 1, Phase 1, Phase 2. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.
Browse More
All United States Trials → Global lung cancer Trials → All Countries → All Trials →
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology