To join a lung cancer clinical trial in United States, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in United States directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.

What phases are lung cancer trials in United States?

Active lung cancer trials in United States span Phase 1, Phase 2, Phase 2, Phase 3, Phase 1, Phase 2, EARLY_Phase 1. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: July 2026 · Data Methodology

Active Trials in United States (28)

The Florida ASCENT Study

Prediction Augmented Screening Initiative

Lung Cancer Biomarkers and Screening

Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies

Biomarkers in Patients With Respiratory Tract Dysplasia or Lung Cancer, Head and Neck Cancer, or Aerodigestive Tract Cancer and in Normal Volunteers

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

Pulmonary Rehabilitation in Advanced Lung Cancer Survivors

Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients

Using Ex Vivo Tumoroids To Predict Immunotherapy Response In NSCLC

Improving Care for Rural Patients With Solid Tumors

EXoPERT EMERALD Clinical Study

Study of CTDNA Response Adaptive Immuno-Chemotherapy in Lung Cancer

MRI and Biomarkers for Lung Nodules Detected During Lung Cancer Screening

Mobile Application to Improve Health-Related Outcomes in Patients With Advanced Lung Cancer

Investigating Hereditary Risk In Thoracic Cancers (INHERIT)

Adaptive Symptom Self-Management Immunotherapy Study

Safety and Efficacy of OBX-115 in Advanced Solid Tumors

Couple-Based Meditation for Metastatic Lung Cancer Patients and Their Partners

A Patient and Provider Intervention to Address Health Disparities in Lung Cancer Screening

Rural Illinois Lung Cancer Screening Initiative

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Immunobiology Blood and Tissue Collection of Upper Aerodigestive Malignancies

Testing the Safety of Dapagliflozin Prior to Surgery for the Treatment of Patients With Stage IA Lung Adenocarcinoma

Social Optimization Study

Studying Tumor Tissue Samples and Blood Samples to Learn More About DNA Changes in Patients With Lung Cancer

Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

A Study of a Side Effects and Resource Navigation Program for People With Cancer

ATATcH Alternating Treatment Plans for Advanced Cancer

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