To join a lung cancer clinical trial in United States, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in United States directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.

What phases are lung cancer trials in United States?

Active lung cancer trials in United States span Phase 2, Phase 1. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology

Active Trials in United States (26)

Implementation and Effectiveness of the BJC-Pink and Pearl Project on Lung Cancer Screening

A Study of a Side Effects and Resource Navigation Program for People With Cancer

Adding Certolizumab to Chemotherapy + Nivolumab in People Who Have Lung Cancer That Can Be Treated With Surgery

Axelopran for Advanced Cancer in Patients Receiving Opioids

Using Ex Vivo Tumoroids To Predict Immunotherapy Response In NSCLC

The SENTINL-1 Study: Evaluating Patient-Reported Outcomes of AI-Inferred Lung Cancer Risk

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

Accelerated Pulmonary Rehabilitation in the Preoperative Period

Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

PROGRESS: Precision Oncology Using Genomic Reflexive Evaluations for Study Selection and Survival

Confocal Laser Endomicroscopy VERification

Study Comparing Two Different Schedules of Radiation for Early-stage Lung Cancer

Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancer

Preliminary Efficacy of Different Exercise Training During Immunotherapy in Patients With Lung Cancer: The ENHANCE Trial

REStoring lymphoCytes Using NKTR-255* After chemoradiothErapy in Solid Tumors (RESCUE)

Image Guided VATS vs. VATS Resection

Centralized Screening Unit (CSU) at Montefiore-Einstein

Adaptation and Pilot Testing of a Lung Cancer Screening Decision Aid for Patients From a Safety-Net Healthcare System

Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial

A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies

Goals of Care Discussion for Patients With Advanced Lung and Gastrointestinal Cancer in the Emergency Department of a Comprehensive Cancer Center

IDOV-Immune for Advanced Solid Tumors

CHAMP Lung Cancer Screening Program

Precision Lung Cancer Survivorship Care Intervention

Next Generation Chest X-Ray Tomosynthesis for Screening of Lung Cancer

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