🇺🇸 United States Country × Condition
heart failure Clinical Trials in United States
Active clinical trials for heart failure with research sites in United States. All data sourced live from ClinicalTrials.gov — updated daily.
Active Trials: 24 // Recruiting: 24 Phases: Phase 1, Phase 2, Phase 1 // Updated: Daily
Total Trials
24
Recruiting Now
24
Country
🇺🇸 United States
Active Trials in United States (24)
NCT06541509 Phase 1, Phase 2
Recruiting
Mechanisms of Semaglutide Therapy in Heart Failure Patients
Enrollment
10 pts
Country
🇺🇸 United States
University Medical Centre Ljubljana
View Trial → NCT06209359 Phase 1
Recruiting
Mechanisms of Diuretic Resistance in Heart Failure, Aim 3
Enrollment
50 pts
Country
🇺🇸 United States
Yale University
View Trial → NCT06349941 Phase 3
Recruiting
Home-based Cardiac Rehabilitation in Heart Failure
Enrollment
332 pts
Country
🇺🇸 United States
University of Texas Southwestern Me...
View Trial → NCT06049420
Recruiting
Lifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients
Enrollment
95 pts
Country
🇺🇸 United States
West Virginia School of Osteopathic...
View Trial → NCT06895070
Recruiting
XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)
Enrollment
60 pts
Country
🇺🇸 United States
XVIVO Perfusion
View Trial → NCT04656080
Recruiting
Cardiopulmonary Stress Testing (CPET) AlloSure Study
Enrollment
27 pts
Country
🇺🇸 United States
Baylor Research Institute
View Trial → NCT04703842 Phase 1, Phase 2
Recruiting
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction
Enrollment
57 pts
Country
🇺🇸 United States
Sardocor Corp.
View Trial → NCT06195059
Recruiting
Contrast Echocardiography During Exercise to Assess Pulmonary Blood Volume
Enrollment
800 pts
Country
🇺🇸 United States
Mayo Clinic
View Trial → NCT03822442
Recruiting
MRI to Predict Rejection and Failure in Transplant and Cardiomyopathy Patients
Enrollment
200 pts
Country
🇺🇸 United States
Children's National Research Instit...
View Trial → NCT04419480
Recruiting
Hemodynamic Monitoring to Prevent Adverse Events foLlowing cardiOgenic Shock Trial
Enrollment
40 pts
Country
🇺🇸 United States
Inova Health Care Services
View Trial → NCT06859970
Recruiting
An Early Feasibility Study Evaluation of an Implant Free Interatrial Shunt to Improve Heart Failure
Enrollment
20 pts
Country
🇺🇸 United States
InterShunt Technologies, Inc.
View Trial → NCT05839067
Recruiting
Supporting Health in Veterans With Heart Failure
Enrollment
100 pts
Country
🇺🇸 United States
Florida State University
View Trial → NCT06733012
Recruiting
Splanchnic X: Splanchnic Nerve Block in Heart Failure With Reduced Ejection Fraction
Enrollment
54 pts
Country
🇺🇸 United States
Duke University
View Trial → NCT06378632
Recruiting
AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM
Enrollment
500 pts
Country
🇺🇸 United States
Cordio Medical
View Trial → NCT06052072
Recruiting
Pulmonary Artery DenerVation Clinical Study Using the Gradient Denervation System in Heart Failure Patients With Pulmonary Hypertension Group 2 (PreVail-PH2 Study)
Enrollment
50 pts
Country
🇺🇸 United States
Gradient Denervation Technologies
View Trial → NCT05650541
Recruiting
Feasibility and Efficacy Study of the CardioPulmonary Management (CPM) System in Patients With Chronic Heart Failure
Enrollment
1,200 pts
Country
🇺🇸 United States
Analog Device, Inc.
View Trial → NCT06147336
Recruiting
A Multi-center, National, Open-label, Prospective Study to Evaluate the Performance of the V-Lap™ System
Enrollment
10 pts
Country
🇺🇸 United States
Vectorious Medical Technologies Ltd...
View Trial → NCT05323487 Phase 1
Recruiting
Mechanisms of Diuretic Resistance in Heart Failure, Aim 1
Enrollment
75 pts
Country
🇺🇸 United States
Yale University
View Trial → NCT06688396
Recruiting
Dilated Cardiomyopathy Detection Using AI and Screening With Mobile Technology (DCM-DETECT)
Enrollment
150 pts
Country
🇺🇸 United States
Lancaster General Hospital
View Trial → NCT07403669
Recruiting
Cardiovascular Kidney and Metabolic Health Assessment and Patient Empowerment
Enrollment
300 pts
Country
🇺🇸 United States
Aventyn, Inc.
View Trial → NCT06593314
Recruiting
Using Ultromics EchoGo HFpEF Algorithm to Identify and Treat High Heart Failure Risk in Patients With Type 2 Diabetes
Enrollment
800 pts
Country
🇺🇸 United States
University of Texas Southwestern Me...
View Trial → NCT02973633 EARLY_Phase 1
Recruiting
Diffusion MRI in Heart Failure
Enrollment
160 pts
Country
🇺🇸 United States
Massachusetts General Hospital
View Trial → NCT07112924
Recruiting
CCM OPEN HF Registry
Enrollment
5,500 pts
Country
🇺🇸 United States
Impulse Dynamics
View Trial → NCT05753059 Phase 1
Recruiting
Mechanisms of Diuretic Resistance in Heart Failure, Aim 2
Enrollment
50 pts
Country
🇺🇸 United States
Yale University
View Trial → Frequently Asked Questions
How many heart failure clinical trials are active in United States?
There are currently 24 active clinical trials for heart failure with sites in United States, of which 24 are actively recruiting patients.
How can I join a heart failure clinical trial in United States?
To join a heart failure clinical trial in United States, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in United States directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.
What phases are heart failure trials in United States?
Active heart failure trials in United States span Phase 1, Phase 2, Phase 1, Phase 3, EARLY_Phase 1. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.