To join a cancer clinical trial in United States, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in United States directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.

What phases are cancer trials in United States?

Active cancer trials in United States span Phase 1, Phase 2, Phase 1, Phase 2. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology

Active Trials in United States (42)

Establishment of a Lifetime of Cohort of Adults Surviving Childhood Cancer

FOG-001 in Locally Advanced or Metastatic Solid Tumors

Evaluating Personalized Therapeutics Clinic (PTC) on Drug-Drug Interactions and Drug-Gene Interactions

Daily Hand-Held Vibration Therapy

An Open-Label Study of INV-1120 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Advanced Solid Tumors

TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors

A Prospective Single Center, Single Arm, Single-institution Registry That Aims to Assess the Safety and Quality of Life Benefits of Computer-assisted Vacuum Thrombectomy (CAVT) in the Treatment of Cancer Patients With Intermediate Risk Pulmonary Embolism (PE)

Evaluating Genomic Testing in Human Cancer & Outcomes of Targeted Therapies

Correlates of CRCI and Gut Microbiome Dysbiosis; a Pilot Study

ACTIVATE: AI-driven Clinical-trial Trial-Information and Viability Assessment Tool for EHRs

000860: A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

Visual Communication: Digital Tool to Improve the Understanding of Treatment Options for Patients With Cancer and Increase Satisfaction of the Overall Experience for Patients, Caregivers, and Providers

Comprehensive Care for AYA: Needs Assessment Survey

ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors

Digital Phenotyping for Psychosocial Screening in Adolescents and Young Adults With Cancer

A Crowd Sourcing Platform for Patients With Cancer

The Florida ASCENT Study

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

IMmunotherapy: Prospective Assessment of Cannabis Treatment in Cancer

A Phase 1 Study of IM-1617 in Participants With Advanced Cancer

Unified Network for Integrated Fluid Collection at Yale

Lattice Radiotherapy for Dose-Escalated Palliation of Bulky Tumors

Correlation Vitamin D Level to Endocrine Autoimmune Toxicity Due to Immune Checkpoint Inhibitors

My Wellbeing Guide: A Novel Tool for Managing Stress and Improving Quality of Life

Multi-Cancer Early Detection (MCED) of Firefighters

Study of Personalized Cancer Therapy to Determine Response and Toxicity

Morehouse Total Cancer Care Protocol

Cryopreservation of Ovarian Tissue

Cannabis Use Registry to Improve Overall Understanding of Symptoms (CURIOUS)

Survivorship Plan HEalth REcord (SPHERE) Implementation Trial

Association Between Exercise, Patient-Reported Outcomes, and Clinical Events in Adult Cancer Survivors

Occupational Cancer Screening in Firefighters: A Pilot Study Within the Inova Health System

TEMPUS ARIES: A Biobank Registry Platform Study in Oncology

Impact of the Coronavirus (COVID-19) on Patients With Cancer

A Study in Patients With Advanced Cancers

Feasibility of a Real-world, Financial Psycho-oncology Intervention to Address Cancer-related Financial Distress

Study of a Support Program for Quality of Life in Chinese Cancer Patients and Survivors

Virtual Reality Intervention to Improve Psychological Symptom Burden for Cancer Patients Undergoing Treatment

Multi-Cancer Detection Observational Cohort Study

A Study of Music Therapy for Anxiety in People With Cancer

Keep Social Randomized Controlled Trial for Young Adults With Cancer

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