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cancer Clinical Trials in United States

Active clinical trials for cancer with research sites in United States. All data sourced live from ClinicalTrials.gov — updated daily.

Active Trials: 42 // Recruiting: 42 Phases: Phase 2, Phase 2, Phase 3 // Updated: Daily
Total Trials
42
Recruiting Now
42
Country
🇺🇸 United States

Active Trials in United States (42)

NCT06915116 Phase 2
Recruiting

Acupuncture for People Experiencing Period Loss Due to Chemotherapy

Enrollment
60 pts
Country
🇺🇸 United States
Memorial Sloan Kettering Cancer Cen...
View Trial →
NCT05474846 Phase 2, Phase 3
Recruiting

Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer

Enrollment
188 pts
Country
🇺🇸 United States
M.D. Anderson Cancer Center
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NCT07042243
Recruiting

The Florida ASCENT Study

Enrollment
100 pts
Country
🇺🇸 United States
University of Florida
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NCT06090266 Phase 1, Phase 2
Recruiting

A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents

Enrollment
168 pts
Country
🇺🇸 United States
OncoResponse, Inc.
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NCT06577987 Phase 1
Recruiting

Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies

Enrollment
220 pts
Country
🇺🇸 United States
Circle Pharma
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NCT01492036
Recruiting

Long-Term Follow-Up of Recipient of Gene Transfer Research

Enrollment
130 pts
Country
🇺🇸 United States
M.D. Anderson Cancer Center
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NCT05694650
Recruiting

Perceptions of Hospital Care at Home for Patients With Cancer: A Qualitative Study of Cancer Providers, Patients and Caregivers.

Enrollment
20 pts
Country
🇺🇸 United States
M.D. Anderson Cancer Center
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NCT06506435
Recruiting

Radiotherapy Patient Education With Virtual Reality

Enrollment
150 pts
Country
🇺🇸 United States
University of Miami
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NCT05745038
Recruiting

A Single Arm Pilot Trial of a Social Network Intervention

Enrollment
330 pts
Country
🇺🇸 United States
University of Rochester
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NCT05427240
Recruiting

eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Cancer

Enrollment
1,000 pts
Country
🇺🇸 United States
Abramson Cancer Center at Penn Medi...
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NCT01542879 Phase 1, Phase 2
Recruiting

Development of Radiation Free Whole Body Magnetic Resonance (MR) Imaging Technique for Staging Children With Cancer

Enrollment
75 pts
Country
🇺🇸 United States
Heike E Daldrup-Link
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NCT04343157 Phase 2
Recruiting

UCSD Image-Guided Cognitive-Sparing Radiosurgery for Brain Metastases

Enrollment
60 pts
Country
🇺🇸 United States
Jona Hattangadi-Gluth
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NCT05443737 Phase 3
Recruiting

Evaluation of a Telehealth Oncofertility Care Intervention in Adolescent and Young Adult Cancer Patients

Enrollment
2,800 pts
Country
🇺🇸 United States
University of California, San Diego
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NCT06892691
Recruiting

Pleuroscopy First Versus Thoracentesis First in Patients With Suspected Malignant Pleural Effusions

Enrollment
98 pts
Country
🇺🇸 United States
Icahn School of Medicine at Mount S...
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NCT06667427
Recruiting

Pilot Study of Management of Facial Paralysis in the Oncologic Patient: Nerve Transfer Techniques to Improve Facial Function and Quality of Life

Enrollment
40 pts
Country
🇺🇸 United States
M.D. Anderson Cancer Center
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NCT05405413 Phase 2
Recruiting

CAncer TReatment INformed by the Molecular Tumor Board At Dartmouth

Enrollment
192 pts
Country
🇺🇸 United States
Dartmouth-Hitchcock Medical Center
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NCT06644560
Recruiting

A Nutrition & Exercise Prehabilitation Intervention on Inflammatory Biomarkers in AI Cancer Patients

Enrollment
30 pts
Country
🇺🇸 United States
University of Arizona
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NCT03848962
Recruiting

Collection and Distribution of Biospecimens for Novel Research Uses

Enrollment
10,000 pts
Country
🇺🇸 United States
iSpecimen Inc
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NCT07227324
Recruiting

Cannabis Use Registry to Improve Overall Understanding of Symptoms (CURIOUS)

Enrollment
1,000 pts
Country
🇺🇸 United States
HealthPartners Institute
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NCT05454280 Phase 3
Recruiting

Post-Discharge Risk-Based Management in Patients Undergoing High-Risk Elective Major Cancer Operations (PRS II)

Enrollment
880 pts
Country
🇺🇸 United States
Fox Chase Cancer Center
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NCT05912257
Recruiting

Preserving Physical Function in Older Adults With Cancer: Impact of an Optimizing Nutrition Intervention Applied Before and After Surgery

Enrollment
188 pts
Country
🇺🇸 United States
VA Office of Research and Developme...
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NCT05166694
Recruiting

Evaluating Personalized Therapeutics Clinic (PTC) on Drug-Drug Interactions and Drug-Gene Interactions

Enrollment
1,300 pts
Country
🇺🇸 United States
University of Chicago
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NCT07305740
Recruiting

On-Trac: An Online Intervention for Cancer Survivors Managing Anxiety

Enrollment
80 pts
Country
🇺🇸 United States
Dana-Farber Cancer Institute
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NCT07167381
Recruiting

xDRIVE for Florida-based Cancer Patients

Enrollment
210 pts
Country
🇺🇸 United States
First Ascent Biomedical Inc.
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NCT04452825
Recruiting

A New Psychotherapy Intervention for Older Cancer Patients

Enrollment
459 pts
Country
🇺🇸 United States
Memorial Sloan Kettering Cancer Cen...
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NCT03943004 Phase 1
Recruiting

Trial of DFP-14927 in Advanced Solid Tumors

Enrollment
30 pts
Country
🇺🇸 United States
Delta-Fly Pharma, Inc.
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NCT06892158
Recruiting

Massage Impact on Sleep in Pediatric Oncology

Enrollment
70 pts
Country
🇺🇸 United States
Children's Hospital of Philadelphia
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NCT06206941
Recruiting

IMmunotherapy: Prospective Assessment of Cannabis Treatment in Cancer

Enrollment
450 pts
Country
🇺🇸 United States
State University of New York at Buf...
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NCT07290309
Recruiting

Survivors Uniting for Remote Guided Exercise

Enrollment
300 pts
Country
🇺🇸 United States
Colorado State University
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NCT00872495
Recruiting

Evaluation of Non-Invasive Assays for the Detection of Urothelial Cancer

Enrollment
500 pts
Country
🇺🇸 United States
Lahey Clinic
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NCT06908629
Recruiting

Addressing Social Determinants of Health Among Metro Detroit Cancer Survivors

Enrollment
120 pts
Country
🇺🇸 United States
Barbara Ann Karmanos Cancer Institu...
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NCT06877884
Recruiting

A Prospective Registry to Enable Collection of Standardized Routine Care Oncology Patient Data

Enrollment
20,000 pts
Country
🇺🇸 United States
N-Power Medicine
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NCT07091968
Recruiting

Feasibility of a Technology-Based Intervention for Depression Referral Uptake in Cancer Survivors

Enrollment
60 pts
Country
🇺🇸 United States
Medical University of South Carolin...
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NCT06440005 Phase 1
Recruiting

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

Enrollment
80 pts
Country
🇺🇸 United States
Angiex, Inc.
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NCT05294991
Recruiting

Wellness App for Sleep Disturbance in Hematological Cancer Patients

Enrollment
276 pts
Country
🇺🇸 United States
The University of Texas Health Scie...
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NCT07030686
Recruiting

Association Between Exercise, Patient-Reported Outcomes, and Clinical Events in Adult Cancer Survivors

Enrollment
1,000 pts
Country
🇺🇸 United States
Memorial Sloan Kettering Cancer Cen...
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NCT06409065
Recruiting

Psycho-Spiritual Management for Patients With Advanced Cancer and Their Family Caregivers

Enrollment
400 pts
Country
🇺🇸 United States
M.D. Anderson Cancer Center
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NCT05919264 Phase 1, Phase 2
Recruiting

FOG-001 in Locally Advanced or Metastatic Solid Tumors

Enrollment
595 pts
Country
🇺🇸 United States
Parabilis Medicines, Inc.
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NCT06242964
Recruiting

The PRISM-Social Needs (PRISM-SN) Intervention for Adolescents and Young Adults With Cancer

Enrollment
100 pts
Country
🇺🇸 United States
Seattle Children's Hospital
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NCT07578571 Phase 1
Recruiting

A Phase 1 Study of IM-1617 in Participants With Advanced Cancer

Enrollment
175 pts
Country
🇺🇸 United States
Immunome, Inc.
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NCT06571305
Recruiting

FAMILY Sleep Program

Enrollment
12 pts
Country
🇺🇸 United States
University of Miami
View Trial →
NCT02872532
Recruiting

Testicular Tissue Cryopreservation in Children

Enrollment
200 pts
Country
🇺🇸 United States
Mayo Clinic
View Trial →

Frequently Asked Questions

How many cancer clinical trials are active in United States?
There are currently 42 active clinical trials for cancer with sites in United States, of which 42 are actively recruiting patients.
How can I join a cancer clinical trial in United States?
To join a cancer clinical trial in United States, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in United States directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.
What phases are cancer trials in United States?
Active cancer trials in United States span Phase 2, Phase 2, Phase 3, Phase 1, Phase 2, Phase 1, Phase 3. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.
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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology