To join a cancer clinical trial in United States, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in United States directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.

What phases are cancer trials in United States?

Active cancer trials in United States span Phase 3, Phase 2, Phase 1, Phase 1, Phase 2. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology

Active Trials in United States (37)

FAMILY Sleep Program

Total Cancer Care Protocol: A Lifetime Partnership With Patients Who Have or May be at Risk of Having Cancer

Evaluation of a Telehealth Oncofertility Care Intervention in Adolescent and Young Adult Cancer Patients

Cancer and Mild Cognitive Impairment Dyadic Intervention

My Wellbeing Guide: A Novel Tool for Managing Stress and Improving Quality of Life

Examining the Feasibility and Impact of a Clinic-based Food Farmacy and Digital Culinary Medicine Program Among Cancer Survivors Treated in a Safety Net Hospital

Multi-Cancer Detection Observational Cohort Study

Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE)

Improving Outcomes in Early Menopause After Cancer

Digital Intervention for Symptom Management in Cancer and Opioid Sparing Using Virtual Reality (DISCOVR) Study

UCSD Image-Guided Cognitive-Sparing Radiosurgery for Intracranial Lesions

eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Cancer

Light Therapy for Chemotherapy Induced Peripheral Neuropathy in Childhood Cancer Survivors

Supportive Care Intervention for Outpatient Stem Cell Transplant Patients

A Study of Herbal Supplements in Cancer Survivors With Constipation

Patient Derived Preclinical Models

Long-Term Follow-Up of Recipient of Gene Transfer Research

Feasibility and Acceptability of Wearable Sensors and ePROs in Early Phase Clinical Trials

Modernizing Instructions to Improve Treatment Participation of Subjects During Their First Radiotherapy

Discovering New Genetic Markers in Adults and Children Who May Be At Risk for Hereditary Forms of Cancer

Survivors Uniting for Remote Guided Exercise

Morehouse Total Cancer Care Protocol

A New Psychotherapy Intervention for Older Cancer Patients

Testicular Tissue Cryopreservation for Fertility Preservation

Pilot Study of Management of Facial Paralysis in the Oncologic Patient: Nerve Transfer Techniques to Improve Facial Function and Quality of Life

A Study of Shengbai Oral Formula to Assess Safety and Alleviation of Adverse Effects in Cancer Patients Undergoing Chemotherapy

An Observational Study On TheAccuracy Of Whole-Body Magnetic Resonance Imaging (Wb-Mri) ScreeningTo Predict Clinically Significant Diagnoses In General Population Subjects Interested In Proactive And Advanced General Preventive Healthcare.

A Natural History Study of Metabolic Sizing in Health and Disease

The ECOG-ACRIN SUPPORT Trial: Multilevel Intervention to Improve Diverse Enrollment in Cancer Clinical Trials

Phase I Study of SYS6043 in Patients With Advanced/Metastatic Solid Tumors

Spiritual Care or Psychotherapy Versus Palliative Care Alone in Patients With Non-Curative Malignancies

Occupational Cancer Screening in Firefighters: A Pilot Study Within the Inova Health System

Enhancing Motivation to Quit Smoking Via Self-Help Intervention Targeted to Cancer Type

A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors

TEMPUS ARIES: A Biobank Registry Platform Study in Oncology

Isa-Rd for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma

A Study in Patients With Advanced Cancers

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