To join a alzheimer disease clinical trial in United States, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in United States directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.

What phases are alzheimer disease trials in United States?

Active alzheimer disease trials in United States span Phase 4, Phase 2, Phase 1, Phase 2, Phase 1, Phase 3. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.

Browse More

All United States Trials → Global alzheimer disease Trials → All Countries → All Trials →

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: July 2026 · Data Methodology

Active Trials in United States (23)

A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)

UAB Alzheimer's Disease Center Core Cohort - Imaging Substudy

Longitudinal Early-onset Alzheimer's Disease Study Protocol

Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide Riboside

Gamma Light and Sound Stimulation to Prevent Dementia in Cognitively Normal People at Risk for Alzheimer's Disease

Exercise to Improve Brain Health in Older African Americans

First-in-Human Evaluation of an Astrocytic Glutamate Transporter (EAAT2) PET Tracer in Dementia

TREAD: Time Restricted Eating Intervention for Alzheimer's Disease

I-CARE 2: Mobile Telehealth to Reduce Alzheimer'S-related Symptoms

Vestibular Therapy in Alzheimer's Disease

Alzheimer Prevention Trials (APT) Webstudy

Paper-Based and Smartphone-Based Memory Supports

Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy

Brain Energy for Amyloid Transformation in Alzheimer's Disease Study

Cardiac-Control Affecting Learning Through Mindfulness (CALM)

Early Age-Related Hearing Loss Investigation (EARHLI)

Improving Access to Care for Veterans With Memory Loss

ADRC Clinical Cohort (Alzheimer's Disease)

Repurposing Siponimod for Alzheimer's Disease

Individual Closed-Loop Neuromodulation Therapy for Alzheimer's Disease

A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)

MR Evaluation of Cerebrospinal Fluid (CSF) Dynamics

Tele-Savvy for Latino Caregivers

Frequently Asked Questions