To join a alzheimer disease clinical trial in United States, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in United States directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.

What phases are alzheimer disease trials in United States?

Active alzheimer disease trials in United States span Phase 2, EARLY_Phase 1, Phase 1, Phase 4. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.

Browse More

All United States Trials → Global alzheimer disease Trials → All Countries → All Trials →

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology

Active Trials in United States (20)

Senicapoc in Alzheimer's Disease

Investigation of Inflammation in Alzheimer's Disease and Related Dementias (ADRD) Using [11C]-CS1P1

Cognitive Neurology Unit Clinical Registry

Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease

Bumetanide in Patients With Alzheimer's Disease

Ultralow Dose PET Imaging of 18F-Florbetapir, 18F-Flutemetamol

A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease

ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults

ADRC Clinical Cohort (Alzheimer's Disease)

Alzheimer"s Imaging Biomarkers in Obesity

AV-1980R (Tau Vaccine) in Preclinical Alzheimer's Disease (TAURUS-1980)

Computerized Tests of Cognitive Decline in Presymptomatic Alzheimer's Disease

A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)

Molecular and Structural Imaging in Alzheimer's Disease: A Longitudinal Study

Cardiac-Control Affecting Learning Through Mindfulness (CALM)

Improving Access to Care for Veterans With Memory Loss

Enhancing Sleep Quality for Nursing Home Residents With Dementia - R33 Phase

Individual Closed-Loop Neuromodulation Therapy for Alzheimer's Disease

Establishing Normal Cognitive Test Scores for Adults Using a Voice-Enabled Digital Testing Platform Across the Lifespan

Cognitive Vulnerability to Stress in Individuals at Risk for Alzheimer's Disease

Frequently Asked Questions