🇺🇸 United States Country × Condition
advanced solid tumor Clinical Trials in United States
Active clinical trials for advanced solid tumor with research sites in United States. All data sourced live from ClinicalTrials.gov — updated daily.
Active Trials: 20 // Recruiting: 20 Phases: Phase 1, Phase 1, Phase 2 // Updated: Daily
Total Trials
20
Recruiting Now
20
Country
🇺🇸 United States
Active Trials in United States (20)
NCT07226349 Phase 1
Recruiting
A Study of BG-75098 Alone and in Combination With Other Agents in Adults With Advanced Solid Tumors
Enrollment
105 pts
Country
🇺🇸 United States
BeOne Medicines
View Trial → NCT06241456 Phase 1
Recruiting
FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibodies in Advanced Solid Tumors
Enrollment
351 pts
Country
🇺🇸 United States
Fate Therapeutics
View Trial → NCT05103683 Phase 1
Recruiting
First in Human Study of TORL-1-23 in Participants With Advanced Cancer
Enrollment
90 pts
Country
🇺🇸 United States
TORL Biotherapeutics, LLC
View Trial → NCT06187402 Phase 1, Phase 2
Recruiting
A Study of LM-24C5 For Advanced Solid Tumors
Enrollment
49 pts
Country
🇺🇸 United States
LaNova Medicines Limited
View Trial → NCT05661461 Phase 1
Recruiting
Dose-escalation Study to Assess Safety and Pharmacokinetics of Nab-Sirolimus in Patients With Locally Advanced or Metastatic Solid Tumors and Moderate Liver Impairment
Enrollment
28 pts
Country
🇺🇸 United States
Aadi Bioscience, Inc.
View Trial → NCT07414836 Phase 1
Recruiting
A First-in-Human Study of BG-C0979 in Adults With Advanced Solid Tumors
Enrollment
84 pts
Country
🇺🇸 United States
BeOne Medicines
View Trial → NCT07181681 Phase 1
Recruiting
A First-in-Human Study of BG-C0902 Alone and in Combination With Other Therapeutic Agents in Patients With Advanced Solid Tumors
Enrollment
63 pts
Country
🇺🇸 United States
BeOne Medicines
View Trial → NCT05875168 Phase 1, Phase 2
Recruiting
First-in-Human Study of DS-3939a in Participants With Advanced Solid Tumors
Enrollment
590 pts
Country
🇺🇸 United States
Daiichi Sankyo
View Trial → NCT05892718 Phase 1
Recruiting
A Safety and Efficacy Study of HCB101, Fc-fusion Protein Targeting SIRPα-CD47 Pathway, in Solid or Hematological Tumors
Enrollment
80 pts
Country
🇺🇸 United States
FBD Biologics Limited
View Trial → NCT04104776 Phase 1, Phase 2
Recruiting
A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas
Enrollment
300 pts
Country
🇺🇸 United States
Novartis Pharmaceuticals
View Trial → NCT05269316 Phase 1, Phase 2
Recruiting
Study to Evaluate IMP9064 as a Monotherapy or in Combination in Patients With Advanced Solid Tumors
Enrollment
61 pts
Country
🇺🇸 United States
Impact Therapeutics, Inc.
View Trial → NCT06242470 Phase 1
Recruiting
A Study of MGC026 in Participants With Advanced Solid Tumors
Enrollment
250 pts
Country
🇺🇸 United States
MacroGenics
View Trial → NCT07284186 Phase 1
Recruiting
First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors
Enrollment
155 pts
Country
🇺🇸 United States
Plexium, Inc.
View Trial → NCT05873686 Phase 1
Recruiting
A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers
Enrollment
140 pts
Country
🇺🇸 United States
Nuvectis Pharma, Inc.
View Trial → NCT06132503 Phase 1
Recruiting
Safety, Pharmacokinetics, and Clinical Activity of LP-284 in Adult Patients With Relapsed or Refractory Lymphomas and Solid Tumors
Enrollment
110 pts
Country
🇺🇸 United States
Lantern Pharma Inc.
View Trial → NCT07213830 Phase 1, Phase 2
Recruiting
A Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Anti-tumour Activity of IPN01203 in Adults With Locally Advanced or Metastatic Solid Tumours Exposed to Immune Checkpoint Inhibitor Therapies
Enrollment
102 pts
Country
🇺🇸 United States
Ipsen
View Trial → NCT05765851 Phase 1
Recruiting
A Study of DS-1103a Combination Therapy in Participants With Advanced Solid Tumors
Enrollment
108 pts
Country
🇺🇸 United States
Daiichi Sankyo
View Trial → NCT04390737 Phase 1, Phase 2
Recruiting
Evaluate the Safety and Clinical Activity of HH2853
Enrollment
254 pts
Country
🇺🇸 United States
Haihe Biopharma Co., Ltd.
View Trial → NCT05320588 Phase 1, Phase 2
Recruiting
A Study in Patients With Advanced Cancers
Enrollment
332 pts
Country
🇺🇸 United States
BiOneCure Therapeutics Inc.
View Trial → NCT05417321 Phase 1, Phase 2
Recruiting
A Study Evaluating the Safety and Efficacy of HB0036 in Subjects With Advanced Solid Tumors
Enrollment
80 pts
Country
🇺🇸 United States
Shanghai Huaota Biopharmaceutical C...
View Trial → Frequently Asked Questions
How many advanced solid tumor clinical trials are active in United States?
There are currently 20 active clinical trials for advanced solid tumor with sites in United States, of which 20 are actively recruiting patients.
How can I join a advanced solid tumor clinical trial in United States?
To join a advanced solid tumor clinical trial in United States, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in United States directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.
What phases are advanced solid tumor trials in United States?
Active advanced solid tumor trials in United States span Phase 1, Phase 1, Phase 2. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology