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acute myeloid leukemia Clinical Trials in United States

Active clinical trials for acute myeloid leukemia with research sites in United States. All data sourced live from ClinicalTrials.gov — updated daily.

Active Trials: 24 // Recruiting: 24 Phases: Phase 2, Phase 1 // Updated: Daily
Total Trials
24
Recruiting Now
24
Country
🇺🇸 United States

Active Trials in United States (24)

NCT04195633 Phase 2
Recruiting

Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies

Enrollment
60 pts
Country
🇺🇸 United States
Fred Hutchinson Cancer Center
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NCT05875805
Recruiting

A Telehealth Advance Care Planning Intervention

Enrollment
207 pts
Country
🇺🇸 United States
University of Rochester
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NCT05031897 Phase 2
Recruiting

Two Step Haplo With Radiation Conditioning

Enrollment
63 pts
Country
🇺🇸 United States
Thomas Jefferson University
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NCT06440135 Phase 1
Recruiting

Ziftomenib Maintenance Post Allo-HCT

Enrollment
22 pts
Country
🇺🇸 United States
Massachusetts General Hospital
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NCT03471260 Phase 1, Phase 2
Recruiting

Ivosidenib and Venetoclax With or Without Azacitidine in Treating Patients With IDH1 Mutated Hematologic Malignancies

Enrollment
96 pts
Country
🇺🇸 United States
M.D. Anderson Cancer Center
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NCT06195891 Phase 1
Recruiting

Orca-T Following Chemotherapy and Total Marrow and Lymphoid Irradiation for the Treatment of Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia or Myelodysplastic Syndrome

Enrollment
33 pts
Country
🇺🇸 United States
City of Hope Medical Center
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NCT06575296 Phase 1
Recruiting

Revumenib for the Treatment of Acute Leukemia in Patients Post-Allogeneic Stem Cell Transplant

Enrollment
27 pts
Country
🇺🇸 United States
City of Hope Medical Center
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NCT05334069
Recruiting

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

Enrollment
2,000 pts
Country
🇺🇸 United States
Alliance for Clinical Trials in Onc...
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NCT05184842 Phase 2
Recruiting

Metabolically Optimized, Non-cytotoxic Low Dose Weekly Decitabine/Venetoclax in MDS and AML

Enrollment
91 pts
Country
🇺🇸 United States
Montefiore Medical Center
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NCT07356154 Phase 1, Phase 2
Recruiting

A Study of Revumenib and Mezigdomide in People With Leukemia

Enrollment
52 pts
Country
🇺🇸 United States
Memorial Sloan Kettering Cancer Cen...
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NCT05401097 Phase 2
Recruiting

IDH Targeted/Non- Targeted vs Non-targeted/IDH-targeted Approaches in the Treatment of Newly Diagnosed IDH Mutated AML Patients Not Candidates for Intensive Induction Therapy (I- DATA Study)

Enrollment
125 pts
Country
🇺🇸 United States
Alice Mims
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NCT06928662 Phase 1, Phase 2
Recruiting

Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of Relapse

Enrollment
36 pts
Country
🇺🇸 United States
Fred Hutchinson Cancer Center
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NCT05101551 Phase 1
Recruiting

Study of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and Efficacy

Enrollment
34 pts
Country
🇺🇸 United States
Norman J. Lacayo
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NCT04293562 Phase 3
Recruiting

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

Enrollment
1,186 pts
Country
🇺🇸 United States
Children's Oncology Group
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NCT06514261 Phase 1
Recruiting

Testing the Combination of an Anti-Cancer Drug, Iadademstat, With Other Anti-Cancer Drugs (Venetoclax and Azacitidine) for Treating AML

Enrollment
45 pts
Country
🇺🇸 United States
National Cancer Institute (NCI)
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NCT06297941 Phase 1
Recruiting

Study of REM-422 in Patients With AML or Higher Risk MDS

Enrollment
100 pts
Country
🇺🇸 United States
Remix Therapeutics
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NCT06824168 Phase 2
Recruiting

Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acute Myeloid Leukemia Patients in Complete Remission

Enrollment
130 pts
Country
🇺🇸 United States
Daiichi Sankyo
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NCT03589729 Phase 2
Recruiting

Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancers

Enrollment
100 pts
Country
🇺🇸 United States
M.D. Anderson Cancer Center
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NCT06594445 Phase 1
Recruiting

HM2023-05: GTB-3650 Trike for High Risk MDS and R/R AML

Enrollment
45 pts
Country
🇺🇸 United States
Masonic Cancer Center, University o...
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NCT02115295 Phase 2
Recruiting

Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia

Enrollment
508 pts
Country
🇺🇸 United States
M.D. Anderson Cancer Center
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NCT05834244 Phase 1
Recruiting

A Phase Ib Trial of Azacitidine, Venetoclax and Allogeneic NK Cells for Acute Myeloid Leukemia (ADVENT-AML)

Enrollment
32 pts
Country
🇺🇸 United States
M.D. Anderson Cancer Center
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NCT04953897 Phase 1
Recruiting

Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Renal Impairment

Enrollment
18 pts
Country
🇺🇸 United States
Taiho Oncology, Inc.
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NCT04811560 Phase 1, Phase 2
Recruiting

A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)

Enrollment
400 pts
Country
🇺🇸 United States
Janssen Research & Development, LLC
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NCT03113643 Phase 1
Recruiting

SL-401 in Combination With Azacitidine or Azacitidine/Venetoclax in Acute Myeloid Leukemia (AML), High-Risk Myelodysplastic Syndrome (MDS) or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

Enrollment
72 pts
Country
🇺🇸 United States
Dana-Farber Cancer Institute
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Frequently Asked Questions

How many acute myeloid leukemia clinical trials are active in United States?
There are currently 24 active clinical trials for acute myeloid leukemia with sites in United States, of which 24 are actively recruiting patients.
How can I join a acute myeloid leukemia clinical trial in United States?
To join a acute myeloid leukemia clinical trial in United States, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in United States directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.
What phases are acute myeloid leukemia trials in United States?
Active acute myeloid leukemia trials in United States span Phase 2, Phase 1, Phase 1, Phase 2, Phase 3. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.
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