🇮🇹 Italy Country × Condition
breast cancer Clinical Trials in Italy
Active clinical trials for breast cancer with research sites in Italy. All data sourced live from ClinicalTrials.gov — updated daily.
Active Trials: 19 // Recruiting: 19 Phases: Phase 4, Phase 1 // Updated: Daily
Total Trials
19
Recruiting Now
19
Country
🇮🇹 Italy
Active Trials in Italy (19)
NCT07030569
Recruiting
RADIomics to Predict HER2 Status And T-DXd Efficacy in Metastatic Breast Cancer: the RADIOSPHER2 Study
Enrollment
500 pts
Country
🇮🇹 Italy
Fondazione IRCCS Istituto Nazionale...
View Trial → NCT06946238
Recruiting
Single-fraction APBI for Early-stage Breast Cancer With Favorable Histological Subtypes (Breast-1F)
Enrollment
311 pts
Country
🇮🇹 Italy
IRCCS San Raffaele
View Trial → NCT05878964
Recruiting
Evaluation of Skin Health and QoL in Pts Receiving Anti-PD1/PDL1/CTLA4 or CDK Inhibitors.
Enrollment
420 pts
Country
🇮🇹 Italy
Fondazione Policlinico Universitari...
View Trial → NCT06906237
Recruiting
Scarless Advanced Breast Extended Oncoplasty: The ScarABEO Study
Enrollment
250 pts
Country
🇮🇹 Italy
Istituto Oncologico Veneto IRCCS
View Trial → NCT07399808
Recruiting
CDK4/6 Inhibitors in Breast Cancer Elderly Patients: an Observational Ambispective Longitudinal Multicenter Study
Enrollment
100 pts
Country
🇮🇹 Italy
Fondazione IRCCS Policlinico San Ma...
View Trial → NCT06274515 Phase 4
Recruiting
A Study to Investigate Mechanisms of Resistance to Breast Cancer Therapies
Enrollment
320 pts
Country
🇮🇹 Italy
Hoffmann-La Roche
View Trial → NCT04075305
Recruiting
The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study
Enrollment
8,000 pts
Country
🇮🇹 Italy
UMC Utrecht
View Trial → NCT06813456
Recruiting
Implementation of Solid Digital PCR to Support Gold-standard Methods for Evaluation of HER2 Amplification Status: Focus on HER2-low Subtype
Enrollment
234 pts
Country
🇮🇹 Italy
IRCCS Azienda Ospedaliero-Universit...
View Trial → NCT06639178
Recruiting
Effectiveness of an N-acetylcysteine and Urea-based Cream in Prevention of Capecitabine-induced HAND-foot Syndrome in Breast Cancer Patients
Enrollment
25 pts
Country
🇮🇹 Italy
Centro di Riferimento Oncologico - ...
View Trial → NCT05983432 Phase 1
Recruiting
Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors
Enrollment
470 pts
Country
🇮🇹 Italy
SystImmune Inc.
View Trial → NCT07395336 Phase 2
Recruiting
Elacestrant and Exemestane for Patients With Pretreated HR+/HER2- Metastatic Breast Cancer and [18F] FES-avid Lesions (COMBINE)
Enrollment
26 pts
Country
🇮🇹 Italy
European Institute of Oncology
View Trial → NCT07111728
Recruiting
Intraoperative Margin Assessment in Breast Cancer With HSI-Raman
Enrollment
104 pts
Country
🇮🇹 Italy
Istituti Clinici Scientifici Mauger...
View Trial → NCT06300125
Recruiting
Percutaneous Cryoablation of Low-risk Early Breast Cancer
Enrollment
234 pts
Country
🇮🇹 Italy
European Institute of Oncology
View Trial → NCT07617025
Recruiting
Prognostic and Predictive Role of Intrinsic Molecular Subtypes in BRCA-associated Breast Cancer
Enrollment
100 pts
Country
🇮🇹 Italy
Angela Toss
View Trial → NCT06610565
Recruiting
Fasting-mimicking Diet Intervention on Side Effects of Aromatase Inhibitors Treatment in Patients With Breast Cancer
Enrollment
60 pts
Country
🇮🇹 Italy
European Institute of Oncology
View Trial → NCT06272799
Recruiting
Tolerability and Efficacy of Adjuvant T-DM1 in Patients with HER2 Positive Breast Cancer After Incomplete Pathological Response to Neoadjuvant Chemotherapy Including Anti-HER2 Agents.
Enrollment
160 pts
Country
🇮🇹 Italy
Regina Elena Cancer Institute
View Trial → NCT06883201
Recruiting
Application of Patient Blood Management in the Oncology Patient Affected by Breast Cancer
Enrollment
78 pts
Country
🇮🇹 Italy
Regina Elena Cancer Institute
View Trial → NCT06028724
Recruiting
A Study on the Prevalence of Clinically Useful Mutations in Solid Tumor Characterized by Next Generation Sequencing Methods on Liquid Biopsy Analysis (POPCORN)
Enrollment
782 pts
Country
🇮🇹 Italy
Centro di Riferimento Oncologico - ...
View Trial → NCT06462963
Recruiting
OligoCare TwiCs (Trials Within Cohorts) Trial Comparing Acute Toxicity in Single-fraction vs Multiple-fraction SBRT for Metastasis-directed Treatment (SPRINT)
Enrollment
302 pts
Country
🇮🇹 Italy
European Organisation for Research ...
View Trial → Frequently Asked Questions
How many breast cancer clinical trials are active in Italy?
There are currently 19 active clinical trials for breast cancer with sites in Italy, of which 19 are actively recruiting patients.
How can I join a breast cancer clinical trial in Italy?
To join a breast cancer clinical trial in Italy, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in Italy directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.
What phases are breast cancer trials in Italy?
Active breast cancer trials in Italy span Phase 4, Phase 1, Phase 2. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology