🇨🇦 Canada Country × Condition
major depressive disorder Clinical Trials in Canada
Active clinical trials for major depressive disorder with research sites in Canada. All data sourced live from ClinicalTrials.gov — updated daily.
Active Trials: 7 // Recruiting: 7 Phases: Phase 2, Phase 3 // Updated: Daily
Total Trials
7
Recruiting Now
7
Country
🇨🇦 Canada
Active Trials in Canada (7)
NCT06480500 Phase 2
Recruiting
i-CBT and IV Ketamine for Suicidality in Treatment-Resistant Depression: A Randomized, Midazolam-Controlled Clinical Trial
Enrollment
110 pts
Country
🇨🇦 Canada
University Health Network, Toronto
View Trial → NCT03601026
Recruiting
Genetic Counselling in the Prevention of Mental Health Consequences of Cannabis Use
Enrollment
120 pts
Country
🇨🇦 Canada
Nova Scotia Health Authority
View Trial → NCT04972136
Recruiting
rTMS for Depression in Young Adults With Autism
Enrollment
80 pts
Country
🇨🇦 Canada
Centre for Addiction and Mental Hea...
View Trial → NCT06086366
Recruiting
Presynaptic Imaging in Major Depressive Episodes After COVID-19
Enrollment
90 pts
Country
🇨🇦 Canada
Centre for Addiction and Mental Hea...
View Trial → NCT06963021 Phase 3
Recruiting
NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Enrollment
200 pts
Country
🇨🇦 Canada
Neurocrine Biosciences
View Trial → NCT05527509
Recruiting
Risk and Resiliency Factors in the RCMP: A Prospective Investigation
Enrollment
960 pts
Country
🇨🇦 Canada
University of Regina
View Trial → NCT05017311 Phase 4
Recruiting
Optimized Predictive Treatment In Medications for Unipolar Major Depression (OPTIMUM-D)
Enrollment
400 pts
Country
🇨🇦 Canada
Nova Scotia Health Authority
View Trial → Frequently Asked Questions
How many major depressive disorder clinical trials are active in Canada?
There are currently 7 active clinical trials for major depressive disorder with sites in Canada, of which 7 are actively recruiting patients.
How can I join a major depressive disorder clinical trial in Canada?
To join a major depressive disorder clinical trial in Canada, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in Canada directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.
What phases are major depressive disorder trials in Canada?
Active major depressive disorder trials in Canada span Phase 2, Phase 3, Phase 4. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology