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breast cancer Clinical Trials in Canada

Active clinical trials for breast cancer with research sites in Canada. All data sourced live from ClinicalTrials.gov — updated daily.

Active Trials: 14 // Recruiting: 14 Phases: Phase 3, Phase 2 // Updated: Daily
Total Trials
14
Recruiting Now
14
Country
🇨🇦 Canada

Active Trials in Canada (14)

NCT04050423
Recruiting

Investigation of Ultrasound Imaging and Spectroscopy for Characterizing Breast Masses

Enrollment
1,200 pts
Country
🇨🇦 Canada
Sunnybrook Health Sciences Centre
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NCT06911970
Recruiting

Impact of Aerobic Exercise on the Anticancer Immune Response in Patients Receiving Cancer Treatment

Enrollment
44 pts
Country
🇨🇦 Canada
Université de Sherbrooke
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NCT04874038 Phase 3
Recruiting

Prevention of Persistent Pain With LidocAine iNfusions in Breast Cancer Surgery (PLAN)

Enrollment
1,602 pts
Country
🇨🇦 Canada
University Health Network, Toronto
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NCT04680442 Phase 2
Recruiting

Safety of Continuing HER-2 Directed Therapy in Overt Left Ventricular Dysfunction

Enrollment
130 pts
Country
🇨🇦 Canada
Population Health Research Institut...
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NCT06686394 Phase 1, Phase 2
Recruiting

Study of Patritumab Deruxtecan With Other Anticancer Agents in Participants With HER2 Positive Breast Cancer That Has Spread and Cannot Be Surgically Removed (MK-1022-009)

Enrollment
81 pts
Country
🇨🇦 Canada
Merck Sharp & Dohme LLC
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NCT06633380
Recruiting

Alternative Physical Activity Strategies for Breast Cancer Survivors

Enrollment
24 pts
Country
🇨🇦 Canada
University of Toronto
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NCT05601440 Phase 2
Recruiting

Liquid-biopsy Informed Platform Trial to Evaluate CDK4/6-inhibitor Resistant ER+/HER2- Metastatic Breast Cancer

Enrollment
484 pts
Country
🇨🇦 Canada
Canadian Cancer Trials Group
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NCT04874064
Recruiting

TRIple Negative Breast Cancer Markers In Liquid Biopsies Using Artificial Intelligence

Enrollment
130 pts
Country
🇨🇦 Canada
Jewish General Hospital
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NCT05625659
Recruiting

Comparison of Breast Cancer Screening With CESM to DBT in Women With Dense Breasts

Enrollment
2,032 pts
Country
🇨🇦 Canada
American College of Radiology
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NCT04144907
Recruiting

Protein Needs Study

Enrollment
40 pts
Country
🇨🇦 Canada
University of Alberta
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NCT07405801 Phase 2
Recruiting

A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus Ribociclib Plus Fulvestrant in Participants With Advanced Breast Cancer

Enrollment
80 pts
Country
🇨🇦 Canada
Hoffmann-La Roche
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NCT05196087
Recruiting

Non-Invasive Artificial Intelligence-Based Platform MonIToring Program (NIP IT!)

Enrollment
500 pts
Country
🇨🇦 Canada
University Health Network, Toronto
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NCT03053193
Recruiting

MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles

Enrollment
30,000 pts
Country
🇨🇦 Canada
Agendia
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NCT07140172
Recruiting

Axillary Radiotherapy or Axillary Lymph Node Dissection in Patients With Clinically Node- Positive Breast Cancer Undergoing Upfront Tailored Axillary Surgery

Enrollment
1,060 pts
Country
🇨🇦 Canada
University Hospital, Basel, Switzer...
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Frequently Asked Questions

How many breast cancer clinical trials are active in Canada?
There are currently 14 active clinical trials for breast cancer with sites in Canada, of which 14 are actively recruiting patients.
How can I join a breast cancer clinical trial in Canada?
To join a breast cancer clinical trial in Canada, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in Canada directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.
What phases are breast cancer trials in Canada?
Active breast cancer trials in Canada span Phase 3, Phase 2, Phase 1, Phase 2. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.
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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology