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tricuspid regurgitation

Total Trials
9
Recruiting Now
9
Trial Phases
Various

ClinicalMetric tracks all active clinical trials for tricuspid regurgitation sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — tricuspid regurgitation Clinical Trials

How many clinical trials are currently recruiting for tricuspid regurgitation?
ClinicalMetric currently tracks 9 actively recruiting clinical trials for tricuspid regurgitation, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 9. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for tricuspid regurgitation?
tricuspid regurgitation research spans multiple clinical trial phases. Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a tricuspid regurgitation clinical trial?
Eligibility criteria for tricuspid regurgitation trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Top Sponsors
Edwards Lifesciences 1 trial
Haiyan Wang 1 trial
Hangzhou Valgen Medtech Co., Ltd 1 trial
Tangent Cardiovascular Inc. 1 trial
Robert Bosch Medical Center 1 trial

Recruiting Clinical Trials

NCT06833476
Recruiting
TTVR STRONG Under Coverage With Evidence Development (CED) Study
Enrollment
2,044 pts
Location
United States
Sponsor
Edwards Lifesciences
View Trial →
NCT06922526
Recruiting
Pacemaker-related Tricuspid Regurgitation Progression and Long-term Outcomes
Enrollment
200 pts
Location
China
Sponsor
Haiyan Wang
View Trial →
NCT05556460
Recruiting
Safety and Effectiveness Study of DragonFly-T System for Severe Tricuspid Regurgitation
Enrollment
236 pts
Location
China
Sponsor
Hangzhou Valgen Medtech Co., L...
View Trial →
NCT07140562
Recruiting
Safety and Feasibility Study: Transcatheter Valve Repair in Severe Symptomatic Functional Tricuspid Regurgitation
Enrollment
25 pts
Location
Paraguay
Sponsor
Tangent Cardiovascular Inc.
View Trial →
NCT07464106
Recruiting
Evaluation of the Impact of Interventional Treatments for Symptomatic, Severe Tricuspid Valve Insufficiency on Renal Integrity and Function, as Well as on Physical Function and Activity in Older Adults.
Enrollment
100 pts
Location
Germany
Sponsor
Robert Bosch Medical Center
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NCT05848284
Recruiting
Clinical Safety and Efficacy of the VDyne Transcatheter Tricuspid Valve Replacement System for the Treatment of Tricuspid Regurgitation ( VISTA-US)
Enrollment
30 pts
Location
United States, Canad...
Sponsor
VDyne, Inc.
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NCT06307262
Recruiting
European Registry of Transcatheter Repair for Tricuspid Regurgitation
Enrollment
3,000 pts
Location
Germany
Sponsor
LMU Klinikum
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NCT03692598
Recruiting
Study of Transcatheter Tricuspid Annular Repair
Enrollment
60 pts
Location
Denmark, Hungary, La...
Sponsor
Micro Interventional Devices
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NCT07172477
Recruiting
Early Phase Study Using the 'Pivot Extend' System as a Treatment for Patients With Tricuspid Regurgitation
Enrollment
10 pts
Location
Australia
Sponsor
Tau Medical Australia Pty Ltd
View Trial →

Related Conditions

pacemaker (1) tricuspid regurgitation functional (1) tricuspid regurgitation tr (1) tricuspid valve insufficiency (1) cardio renal syndrome (1) frailty (1) tricuspid valve disease (1) tricuspid valvular disorders (1) valvular heart disease (1) heart failure (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology