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squamous cell carcinoma of head and neck

Total Trials
7
Recruiting Now
7
Trial Phases
Phase 1, Phase 1, Phase 2, Phase 2

ClinicalMetric tracks all active clinical trials for squamous cell carcinoma of head and neck sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — squamous cell carcinoma of head and neck Clinical Trials

How many clinical trials are currently recruiting for squamous cell carcinoma of head and neck?
ClinicalMetric currently tracks 7 actively recruiting clinical trials for squamous cell carcinoma of head and neck, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 7. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for squamous cell carcinoma of head and neck?
squamous cell carcinoma of head and neck research spans Phase 1 (4 trials), Phase 2 (3 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a squamous cell carcinoma of head and neck clinical trial?
Eligibility criteria for squamous cell carcinoma of head and neck trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
4
Phase 2
3
Top Sponsors
Seagen, a wholly owned subsidiary of Pfizer 1 trial
Medicenna Therapeutics, Inc. 1 trial
University Health Network, Toronto 1 trial
Bicara Therapeutics 1 trial
IO Biotech 1 trial

Recruiting Clinical Trials

NCT04389632 Phase 1
Recruiting
A Study of Sigvotatug Vedotin in Advanced Solid Tumors
Enrollment
1,006 pts
Location
United States, Franc...
Sponsor
Seagen, a wholly owned subsidi...
View Trial →
NCT05086692 Phase 1, Phase 2
Recruiting
A Beta-only IL-2 ImmunoTherapY Study
Enrollment
115 pts
Location
United States, Austr...
Sponsor
Medicenna Therapeutics, Inc.
View Trial →
NCT06085781
Recruiting
A Study of Head and Neck MRI and Tumor Microenvironment Biomarkers
Enrollment
60 pts
Location
Canada
Sponsor
University Health Network, Tor...
View Trial →
NCT04429542 Phase 1
Recruiting
Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
Enrollment
292 pts
Location
United States, Austr...
Sponsor
Bicara Therapeutics
View Trial →
NCT05280314 Phase 2
Recruiting
Phase II Trial of Neoadjuvant and Adjuvant IO102-IO103 and Pembrolizumab KEYTRUDA® in Patients With Resectable Tumors
Enrollment
60 pts
Location
United States, Austr...
Sponsor
IO Biotech
View Trial →
NCT07419464 Phase 2
Recruiting
5-Fluorouracil Response and Optimization STudy (The FROST Trial)
Enrollment
46 pts
Location
United States
Sponsor
Washington University School o...
View Trial →
NCT07219212 Phase 1
Recruiting
A Study of JNJ-90301900 in Combination With Chemoradiation Therapy in Participants With Locally Advanced Head and Neck Squamous Cell Carcinoma
Enrollment
45 pts
Location
United States, Franc...
Sponsor
Johnson & Johnson Enterprise I...
View Trial →

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology