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obesity childhood

Total Trials
6
Recruiting Now
6
Trial Phases
Phase 2

Obesity research has been transformed by the GLP-1 receptor agonist class (semaglutide, tirzepatide), which achieves 15–22% body weight reduction — approaching surgical outcomes — and reduces cardiovascular events in overweight adults. The pipeline now includes amylin analogs, glucose-dependent insulinotropic polypeptide (GIP) agonists, and oral small molecules targeting appetite regulation.

Active trials investigate next-generation GLP-1 combinations, bimagrumab (anti-ActRII for muscle-sparing weight loss), retatrutide, cagrilintide combinations, and gut microbiome modulators. Trials also study weight regain prevention after GLP-1 discontinuation — an emerging clinical challenge.

Obesity trials typically require a BMI ≥30 or ≥27 with weight-related comorbidities; prior bariatric surgery often excludes participants.

Frequently Asked Questions — obesity childhood Clinical Trials

How many clinical trials are currently recruiting for obesity childhood?
ClinicalMetric currently tracks 6 actively recruiting clinical trials for obesity childhood, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 6. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for obesity childhood?
obesity childhood research spans Phase 2 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a obesity childhood clinical trial?
Eligibility criteria for obesity childhood trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 2
1
Top Sponsors
Coordinación de Investigación en Salud, Mexico 1 trial
Instituto de Salud Carlos III 1 trial
Adhera Health, Inc. 1 trial
Children's Hospital Medical Center, Cincinnati 1 trial
University of South Carolina 1 trial

Recruiting Clinical Trials

NCT06847373
Recruiting

Efficacy and Safety of Vitamin D Supplementation in Pediatric Patients with Obesity

Enrollment
40 pts
Location
Mexico
Sponsor
Coordinación de Investigación ...
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NCT06522529
Recruiting

Sumamos Excelencia Project: Implementation of Best Practices in Clinical Practice (Thrid Edition)

Enrollment
400 pts
Location
Spain
Sponsor
Instituto de Salud Carlos III
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NCT06520787
Recruiting

DAta-driven personaLIzation of a digitAl Health Solution to Support Family Caregivers of Children With Chronic Conditions

Enrollment
40 pts
Location
Spain
Sponsor
Adhera Health, Inc.
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NCT06028113 Phase 2
Recruiting

A Novel Obesity Prevention Program for High-Risk Infants in Primary Care

Enrollment
144 pts
Location
United States
Sponsor
Children's Hospital Medical Ce...
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NCT07176234
Recruiting

The LEADS Trial (Linking Exericise for Advancing Daily Stress Management)

Enrollment
330 pts
Location
United States
Sponsor
University of South Carolina
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NCT06682481
Recruiting

Beta-Cell - Liver Interactions in Situations of Modified Beta-Cell Function

Enrollment
50 pts
Location
Switzerland
Sponsor
Philippe Klee, MD-PhD
View Trial →
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology