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nociceptive pain

Total Trials
3
Recruiting Now
3
Trial Phases
Phase 4

Pain clinical trials span acute procedural pain, chronic musculoskeletal pain, neuropathic pain, and cancer-related pain β€” each requiring distinct trial designs and patient-reported outcome instruments. The regulatory demand for non-opioid alternatives has intensified the search for novel analgesic mechanisms, particularly ion channel targets and neurostimulation approaches.

Active trials evaluate Nav1.7/1.8 blockers, CGRP antagonists for new indications, spinal cord stimulation refinements, virtual reality-based pain management, and patient-specific ketamine infusion protocols. Pain trials increasingly use ecological momentary assessment (EMA) diary approaches over traditional recall-based pain rating scales.

Frequently Asked Questions — nociceptive pain Clinical Trials

How many clinical trials are currently recruiting for nociceptive pain?
ClinicalMetric currently tracks 3 actively recruiting clinical trials for nociceptive pain, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 3. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for nociceptive pain?
nociceptive pain research spans Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a nociceptive pain clinical trial?
Eligibility criteria for nociceptive pain trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 4
1
Top Sponsors
ETH Zurich 1 trial
Ciusss de L'Est de l'Île de Montréal 1 trial
Université Catholique de Louvain 1 trial

Recruiting Clinical Trials

NCT06044584
Recruiting

Unveiling Physiological and Psychosocial Pain Components with an Artificial Intelligence Based Telemonitoring Tool

Enrollment
150 pts
Location
Italy, Switzerland
Sponsor
ETH Zurich
View Trial →
NCT06291363 Phase 4
Recruiting

Impact of Administration of Esmolol on Nociception Level-guided Control of Nociception.

Enrollment
64 pts
Location
Canada
Sponsor
Ciusss de L'Est de l'Île de Mo...
View Trial →
NCT06367777
Recruiting

Cervical/Thoracic Neuromodulation and Nociceptive Processing

Enrollment
24 pts
Location
Belgium
Sponsor
Université Catholique de Louva...
View Trial →
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology