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musculoskeletal pain
Total Trials
6
Recruiting Now
6
Trial Phases
Various
Pain clinical trials span acute procedural pain, chronic musculoskeletal pain, neuropathic pain, and cancer-related pain β€” each requiring distinct trial designs and patient-reported outcome instruments. The regulatory demand for non-opioid alternatives has intensified the search for novel analgesic mechanisms, particularly ion channel targets and neurostimulation approaches.
Active trials evaluate Nav1.7/1.8 blockers, CGRP antagonists for new indications, spinal cord stimulation refinements, virtual reality-based pain management, and patient-specific ketamine infusion protocols. Pain trials increasingly use ecological momentary assessment (EMA) diary approaches over traditional recall-based pain rating scales.
Frequently Asked Questions — musculoskeletal pain Clinical Trials
How many clinical trials are currently recruiting for musculoskeletal pain?
ClinicalMetric currently tracks 6 actively recruiting clinical trials for musculoskeletal pain, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 6. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for musculoskeletal pain?
musculoskeletal pain research spans multiple clinical trial phases. Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a musculoskeletal pain clinical trial?
Eligibility criteria for musculoskeletal pain trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Top Sponsors
1 trial
1 trial
1 trial
1 trial
1 trial
Recruiting Clinical Trials
NCT06621914
Recruiting
Is Low-load Resistance Training With Blood Flow Restriction Feasible During Rehabilitation of Military Personnel With Lower Limb Injuries? Phase One RCT.
Enrollment
28 pts
Location
United Kingdom
Sponsor
Defence Medical Rehabilitation...
NCT07218757
Recruiting
Phase 1 Pilot of a Pragmatic Trial of EAET for Veterans With Chronic Pain
Enrollment
84 pts
Location
United States
Sponsor
University of California, Los ...
NCT07554664
Recruiting
Central Sensitization, Work-Related Stress, and Musculoskeletal Symptoms in Desk-Based Workers With and Without Migraine
Enrollment
159 pts
Location
Turkey (Türkiye)
Sponsor
Bozok University
NCT06940986
Recruiting
The PROmoting Pain Self-Management (PROs) Trial: Holistic Pain Care in the Military Health System
Enrollment
608 pts
Location
United States
Sponsor
Brooke Army Medical Center
NCT06685094
Recruiting
Translation and Validation of the Upper and Lower Limbs, Pain, Autonomy and Quality of Life Scales in Albanian
Enrollment
300 pts
Location
Spain
Sponsor
Universidad Católica San Anton...
NCT06867757
Recruiting
Targeted Realtime Assessment of Chronic Pain in Youth
Enrollment
500 pts
Location
United States
Sponsor
Stanford University
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: April 2026 · Data Methodology