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mitral regurgitation

Total Trials
7
Recruiting Now
7
Trial Phases
Phase 4

ClinicalMetric tracks all active clinical trials for mitral regurgitation sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — mitral regurgitation Clinical Trials

How many clinical trials are currently recruiting for mitral regurgitation?
ClinicalMetric currently tracks 7 actively recruiting clinical trials for mitral regurgitation, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 7. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for mitral regurgitation?
mitral regurgitation research spans Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a mitral regurgitation clinical trial?
Eligibility criteria for mitral regurgitation trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 4
1
Top Sponsors
LMU Klinikum 2 trials
Ottawa Heart Institute Research Corporation 1 trial
Tioga Cardiovascular, Inc. 1 trial
Chinese Academy of Medical Sciences, Fuwai Hospital 1 trial
Universitätsklinikum Hamburg-Eppendorf 1 trial

Recruiting Clinical Trials

NCT06547788
Recruiting
LEFT ATRIAL MONITORING IN PATIENTS BEFORE AND AFTER MITRAL SURGERY - LAMBDA STUDY
Enrollment
50 pts
Location
Canada
Sponsor
Ottawa Heart Institute Researc...
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NCT06038838
Recruiting
Feasibility Study of the Tioga TMVR System
Enrollment
30 pts
Location
Brazil, Georgia, Lit...
Sponsor
Tioga Cardiovascular, Inc.
View Trial →
NCT07007143 Phase 4
Recruiting
STrategies for Antithrombotic tReatment Following Transcatheter Edge-to-Edge Repair in Patients Without an Indication for Oral Anticoagulant
Enrollment
1,032 pts
Location
China
Sponsor
Chinese Academy of Medical Sci...
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NCT04898335
Recruiting
Tendyne European Experience Registry
Enrollment
400 pts
Location
Austria, Belgium, Fr...
Sponsor
LMU Klinikum
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NCT06634121
Recruiting
Efficacy of MitraCLip Vs. PASCAL for the TrEAtment of MitraL REgurgiTation in an All-comer Population
Enrollment
180 pts
Location
Germany
Sponsor
LMU Klinikum
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NCT04688190
Recruiting
CHoice of OptImal transCatheter trEatment for Mitral Insufficiency Registry
Enrollment
1,000 pts
Location
United States, Austr...
Sponsor
Universitätsklinikum Hamburg-E...
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NCT05655897
Recruiting
Safety and Efficacy of the GeminiOne Transcatheter Valve Edge-to-Edge Repair System in Patients With Moderate-severe or Severe Degenerative Mitral Regurgitation
Enrollment
120 pts
Location
China
Sponsor
Peijia Medical Technology (Suz...
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Related Conditions

mitral valve disease (2) heart failure (2) valvular heart disease (1) mitral annular calcification (1) degenerative mitral valve disease (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology