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mitral regurgitation

Total Trials
4
Recruiting Now
4
Trial Phases
Various

ClinicalMetric tracks all active clinical trials for mitral regurgitation sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — mitral regurgitation Clinical Trials

How many clinical trials are currently recruiting for mitral regurgitation?
ClinicalMetric currently tracks 4 actively recruiting clinical trials for mitral regurgitation, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 4. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for mitral regurgitation?
mitral regurgitation research spans multiple clinical trial phases. Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a mitral regurgitation clinical trial?
Eligibility criteria for mitral regurgitation trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Top Sponsors
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 1 trial
LMU Klinikum 1 trial
Mayra Guerrero 1 trial
HighLife SAS 1 trial

Recruiting Clinical Trials

NCT06797687
Recruiting

Mitral Valve Annulus Assessment, Multimodality Imaging

Enrollment
80 pts
Location
Italy
Sponsor
Fondazione Policlinico Univers...
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NCT06634121
Recruiting

Efficacy of MitraCLip Vs. PASCAL for the TrEAtment of MitraL REgurgiTation in an All-comer Population

Enrollment
180 pts
Location
Germany
Sponsor
LMU Klinikum
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NCT04408430
Recruiting

The MITRAL II Pivotal Trial (Mitral Implantation of TRAnscatheter vaLves).

Enrollment
210 pts
Location
United States, Mexic...
Sponsor
Mayra Guerrero
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NCT04029363
Recruiting

Expanded Study of the HighLife 28mm Trans-septal Trans-catheter Mitral Valve in Patients With Moderate-severe or Severe Mitral Regurgitation and at High Surgical Risk

Enrollment
120 pts
Location
Australia, Belgium, ...
Sponsor
HighLife SAS
View Trial →
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology