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metastatic renal cell carcinoma

Total Trials
5
Recruiting Now
5
Trial Phases
Phase 3, Phase 4, Phase 2

ClinicalMetric tracks all active clinical trials for metastatic renal cell carcinoma sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — metastatic renal cell carcinoma Clinical Trials

How many clinical trials are currently recruiting for metastatic renal cell carcinoma?
ClinicalMetric currently tracks 5 actively recruiting clinical trials for metastatic renal cell carcinoma, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 5. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for metastatic renal cell carcinoma?
metastatic renal cell carcinoma research spans Phase 1 (1 trial), Phase 2 (1 trial), Phase 3 (1 trial), Phase 4 (2 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a metastatic renal cell carcinoma clinical trial?
Eligibility criteria for metastatic renal cell carcinoma trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
1
Phase 2
1
Phase 3
1
Phase 4
2
Top Sponsors
SWOG Cancer Research Network 1 trial
Centre Francois Baclesse 1 trial
Karie Runcie 1 trial
OHSU Knight Cancer Institute 1 trial
Oliver Jonas 1 trial

Recruiting Clinical Trials

NCT04510597 Phase 3
Recruiting
Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial
Enrollment
364 pts
Location
United States
Sponsor
SWOG Cancer Research Network
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NCT07028125 Phase 4
Recruiting
Digital Monitoring of Self-reported Symptoms by Patients Treated With Cabozantinib Plus Nivolumab for Advanced Clear-cell Renal Carcinoma
Enrollment
83 pts
Location
France
Sponsor
Centre Francois Baclesse
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NCT06863311 Phase 2
Recruiting
Trial of Zanzalintinib (XL092) in Combination With Immunotherapy in Patients Who Progress on Adjuvant Therapy in Clear Cell RCC
Enrollment
70 pts
Location
United States
Sponsor
Karie Runcie
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NCT07405086 Phase 4
Recruiting
Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study
Enrollment
160 pts
Location
United States
Sponsor
OHSU Knight Cancer Institute
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NCT05700461 Phase 1
Recruiting
Drug Screening Using Novel IMD in Renal Cell Carcinoma
Enrollment
20 pts
Location
United States
Sponsor
Oliver Jonas
View Trial →

Related Conditions

stage iv renal cell cancer ajcc v8 (2) advanced renal cell carcinoma (2) metastatic clear cell renal cell carcinoma (1) renal cell carcinoma kidney cancer (1) locally advanced (1) clear cell renal cell carcinoma (1) advanced biliary tract carcinoma (1) advanced head and neck squamous cell carcinoma (1) advanced hepatocellular carcinoma (1) advanced lung non small cell carcinoma (1) advanced malignant solid neoplasm (1) advanced melanoma (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology