← Browse by Condition
Medical Condition

major depressive episode

Total Trials
5
Recruiting Now
5
Trial Phases
Phase 3

ClinicalMetric tracks all active clinical trials for major depressive episode sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — major depressive episode Clinical Trials

How many clinical trials are currently recruiting for major depressive episode?
ClinicalMetric currently tracks 5 actively recruiting clinical trials for major depressive episode, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 5. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for major depressive episode?
major depressive episode research spans Phase 3 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a major depressive episode clinical trial?
Eligibility criteria for major depressive episode trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 3
1
Top Sponsors
Centre Hospitalier Universitaire de Nīmes 1 trial
Centre for Addiction and Mental Health 1 trial
University of Texas at Austin 1 trial
NYU Langone Health 1 trial
Massachusetts General Hospital 1 trial

Recruiting Clinical Trials

NCT03646058 Phase 3
Recruiting

Add-on Buprenorphine at Analgesic Doses for the Treatment of Severe Suicidal Ideas During a Major Depressive Episode

Enrollment
180 pts
Location
France
Sponsor
Centre Hospitalier Universitai...
View Trial →
NCT06086366
Recruiting

Presynaptic Imaging in Major Depressive Episodes After COVID-19

Enrollment
90 pts
Location
Canada
Sponsor
Centre for Addiction and Menta...
View Trial →
NCT06523439
Recruiting

Accelerated Intermittent Theta Burst in Treatment-Naive Adolescents

Enrollment
40 pts
Location
United States
Sponsor
University of Texas at Austin
View Trial →
NCT07111390
Recruiting

Feasibility of Home-Based Intermittent 60Hz Light Therapy for Major Depressive Disorder (MDD)

Enrollment
40 pts
Location
United States
Sponsor
NYU Langone Health
View Trial →
NCT04130958
Recruiting

Circuit-Based Approach to Suicide: Biomarkers, Predictors, and Novel Therapeutics

Enrollment
80 pts
Location
United States
Sponsor
Massachusetts General Hospital
View Trial →
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology