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Medical Condition
heart failure with reduced ejection fraction
Total Trials
11
Recruiting Now
11
Trial Phases
Phase 3, Phase 1, EARLY_Phase 1
ClinicalMetric tracks all active clinical trials for heart failure with reduced ejection fraction sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.
Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.
Frequently Asked Questions — heart failure with reduced ejection fraction Clinical Trials
How many clinical trials are currently recruiting for heart failure with reduced ejection fraction?
ClinicalMetric currently tracks 11 actively recruiting clinical trials for heart failure with reduced ejection fraction, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 11. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for heart failure with reduced ejection fraction?
heart failure with reduced ejection fraction research spans Phase 1 (2 trials), Phase 3 (1 trial), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a heart failure with reduced ejection fraction clinical trial?
Eligibility criteria for heart failure with reduced ejection fraction trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1 2
Phase 3 1
Phase 4 1
Top Sponsors
1 trial
1 trial
1 trial
1 trial
1 trial
Recruiting Clinical Trials
NCT06942221
Recruiting
Enrollment
140 pts
Location
Switzerland
Sponsor
University Hospital, Basel, Sw...
NCT06736574 Phase 3
Recruiting
Enrollment
1,800 pts
Location
United States, Canad...
Sponsor
Cytokinetics
NCT06831825 Phase 1
Recruiting
Enrollment
24 pts
Location
United States
Sponsor
Medley Therapeutics
NCT06229678 EARLY_Phase 1
Recruiting
Enrollment
71 pts
Location
United States
Sponsor
The University of Texas Health...
NCT06516562
Recruiting
Enrollment
2,500 pts
Location
Vietnam
Sponsor
University Medical Center Ho C...
NCT06920160
Recruiting
Enrollment
196 pts
Location
Spain
Sponsor
Persei Vivarium
NCT05942287
Recruiting
Enrollment
110 pts
Location
Jersey, United Kingd...
Sponsor
University of Oxford
NCT06526988
Recruiting
Enrollment
2,200 pts
Location
United States
Sponsor
University of Colorado, Denver
NCT06299436
Recruiting
Enrollment
50 pts
Location
United States
Sponsor
Johns Hopkins University
NCT07275931
Recruiting
Enrollment
240 pts
Location
Sweden
Sponsor
Linkoeping University
NCT07631156 Phase 4
Recruiting
Enrollment
80 pts
Location
South Korea
Sponsor
Kyungsub Song
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology