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heart failure with preserved ejection fraction

Total Trials
5
Recruiting Now
5
Trial Phases
Various

ClinicalMetric tracks all active clinical trials for heart failure with preserved ejection fraction sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — heart failure with preserved ejection fraction Clinical Trials

How many clinical trials are currently recruiting for heart failure with preserved ejection fraction?
ClinicalMetric currently tracks 5 actively recruiting clinical trials for heart failure with preserved ejection fraction, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 5. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for heart failure with preserved ejection fraction?
heart failure with preserved ejection fraction research spans multiple clinical trial phases. Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a heart failure with preserved ejection fraction clinical trial?
Eligibility criteria for heart failure with preserved ejection fraction trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Top Sponsors
Medtronic Cardiac Rhythm and Heart Failure 1 trial
University Medical Center Goettingen 1 trial
University of Oxford 1 trial
Ohio State University 1 trial
Samsung Medical Center 1 trial

Recruiting Clinical Trials

NCT05839730
Recruiting
Fast Induced Remodeling in Heart Failure With Preserved Ejection Fraction
Enrollment
105 pts
Location
United States
Sponsor
Medtronic Cardiac Rhythm and H...
View Trial →
NCT06208007
Recruiting
Arterial Stiffening as a Predictor for Diastolic Cardiac Dysfunction and HFpEF
Enrollment
150 pts
Location
Germany
Sponsor
University Medical Center Goet...
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NCT05878912
Recruiting
The Effect of Obesity and Weight Loss in Heart Failure With Preserved Ejection Fraction
Enrollment
120 pts
Location
United Kingdom
Sponsor
University of Oxford
View Trial →
NCT06081543
Recruiting
Ketogenic Diet vs Mixed Diet in Patients With Heart Failure
Enrollment
90 pts
Location
United States
Sponsor
Ohio State University
View Trial →
NCT05490901
Recruiting
The Prognostic Role and Diagnostic Efficacy of Exercise Right Heart Catheterization With a Simultaneous Echocardiography in Patients With Dyspnea on Exertion
Enrollment
400 pts
Location
South Korea
Sponsor
Samsung Medical Center
View Trial →

Related Conditions

concentric hypertrophy (1) cardiovascular morbidity (1) obesity (1) chronic pulmonary thromboembolism disorder (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology