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healthy volunteer
Total Trials
12
Recruiting Now
12
Trial Phases
Phase 1, Phase 2, Phase 4
Clinical trials often recruit healthy volunteers for Phase 1 pharmacokinetic and safety studies, vaccine immunogenicity assessments, and normal physiological reference studies. These trials are essential for establishing safe dose ranges and understanding how drugs behave in the absence of disease before testing in patient populations.
Healthy volunteer studies include first-in-human drug trials, vaccine efficacy (flu, RSV, COVID-19, malaria), microbiome intervention studies, exercise physiology research, and device safety assessments. Compensation is often provided; eligibility typically requires no significant medical history and a negative drug screen.
Healthy volunteer trials require participants to be in good general health with no significant medications. Many exclude smokers, pregnant individuals, and those with recent prior trial participation.
Frequently Asked Questions — healthy volunteer Clinical Trials
How many clinical trials are currently recruiting for healthy volunteer?
ClinicalMetric currently tracks 12 actively recruiting clinical trials for healthy volunteer, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 12. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for healthy volunteer?
healthy volunteer research spans Phase 1 (7 trials), Phase 2 (1 trial), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a healthy volunteer clinical trial?
Eligibility criteria for healthy volunteer trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1 7
Phase 2 1
Phase 4 1
Top Sponsors
2 trials
1 trial
1 trial
1 trial
1 trial
Recruiting Clinical Trials
NCT07439263 Phase 1
Recruiting
Enrollment
32 pts
Location
Australia
Sponsor
Hinge Bio
NCT07349758 Phase 1
Recruiting
Enrollment
24 pts
Location
United States
Sponsor
Johns Hopkins University
NCT07662148 Phase 1
Recruiting
Enrollment
48 pts
Location
United States
Sponsor
Biogen
NCT07038720 Phase 1
Recruiting
Enrollment
124 pts
Location
China
Sponsor
Usynova Pharmaceuticals Ltd.
NCT07566468
Recruiting
Enrollment
110 pts
Location
United States
Sponsor
National Institute of Mental H...
NCT00090662
Recruiting
Enrollment
250 pts
Location
United States
Sponsor
National Institute of Allergy ...
NCT07284563 Phase 2
Recruiting
Enrollment
200 pts
Location
United States
Sponsor
Akiva Mintz
NCT07032558 Phase 1
Recruiting
Enrollment
14 pts
Location
Vietnam
Sponsor
Haiphong University of Medicin...
NCT07791797 Phase 4
Recruiting
Enrollment
160 pts
Location
Australia
Sponsor
RDC Clinical Pty Ltd
NCT06877611 Phase 1
Recruiting
Enrollment
96 pts
Location
Australia
Sponsor
Seismic Therapeutic AU Pty Ltd
NCT07133828 Phase 1
Recruiting
Enrollment
78 pts
Location
United States
Sponsor
Biogen
NCT06846034
Recruiting
Enrollment
30 pts
Location
France
Sponsor
Poitiers University Hospital
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology