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esophageal adenocarcinoma

Total Trials
9
Recruiting Now
9
Trial Phases
Phase 2, Phase 1, Phase 1, Phase 2

ClinicalMetric tracks all active clinical trials for esophageal adenocarcinoma sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — esophageal adenocarcinoma Clinical Trials

How many clinical trials are currently recruiting for esophageal adenocarcinoma?
ClinicalMetric currently tracks 9 actively recruiting clinical trials for esophageal adenocarcinoma, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 9. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for esophageal adenocarcinoma?
esophageal adenocarcinoma research spans Phase 1 (5 trials), Phase 2 (4 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a esophageal adenocarcinoma clinical trial?
Eligibility criteria for esophageal adenocarcinoma trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
5
Phase 2
4
Top Sponsors
Khyber Teaching Hospital 1 trial
I-Mab Biopharma US Limited 1 trial
Pfizer 1 trial
AstraZeneca 1 trial
UMC Utrecht 1 trial

Recruiting Clinical Trials

NCT07125248
Recruiting
Outcomes of a Single Chest Drain vs Two Drains
Enrollment
68 pts
Location
Pakistan
Sponsor
Khyber Teaching Hospital
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NCT07432295 Phase 2
Recruiting
Givastomig Combined With Nivolumab and Chemotherapy in Adults With CLDN18.2 Positive Metastatic Gastric Cancer (GIVA-2)
Enrollment
180 pts
Location
United States, China...
Sponsor
I-Mab Biopharma US Limited
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NCT07090499 Phase 1
Recruiting
A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors
Enrollment
310 pts
Location
United States, Canad...
Sponsor
Pfizer
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NCT06005493 Phase 1, Phase 2
Recruiting
Study of AZD5863 in Adult Participants With Advanced or Metastatic Solid Tumors
Enrollment
280 pts
Location
United States, China...
Sponsor
AstraZeneca
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NCT07359443 Phase 1
Recruiting
Combination of Chemotherapy and Adaptive MR-Guided Radiotherapy to Improve Outcomes in Patients With Esophageal Adenocarcinoma
Enrollment
39 pts
Location
Netherlands
Sponsor
UMC Utrecht
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NCT07544589 Phase 1
Recruiting
A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers
Enrollment
66 pts
Location
United States
Sponsor
Dispatch Biotherapeutics
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NCT07182149 Phase 1
Recruiting
A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors
Enrollment
150 pts
Location
United States
Sponsor
Normunity AccelCo, Inc.
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NCT04114136 Phase 2
Recruiting
Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies
Enrollment
72 pts
Location
United States
Sponsor
Dan Zandberg
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NCT06732388 Phase 2
Recruiting
Itraconazole in Combination With Ablation for the Prevention of Esophageal Cancer in Patients With High-risk Barrett's Esophagus
Enrollment
76 pts
Location
United States
Sponsor
National Cancer Institute (NCI...
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Related Conditions

gastric adenocarcinoma (3) gastric cancer (2) hnscc (2) nsclc (2) pleura effusion (1) esophageal anastomotic leak (1) solid tumor (1) advanced cancer (1) metastatic cancer (1) gastroesophageal junction carcinoma (1) advanced metastatic solid tumors (1) bladder cancer (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology