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esophageal adenocarcinoma

Total Trials
5
Recruiting Now
5
Trial Phases
Phase 1, Phase 2, Phase 1, Phase 2

ClinicalMetric tracks all active clinical trials for esophageal adenocarcinoma sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — esophageal adenocarcinoma Clinical Trials

How many clinical trials are currently recruiting for esophageal adenocarcinoma?
ClinicalMetric currently tracks 5 actively recruiting clinical trials for esophageal adenocarcinoma, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 5. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for esophageal adenocarcinoma?
esophageal adenocarcinoma research spans Phase 1 (2 trials), Phase 2 (4 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a esophageal adenocarcinoma clinical trial?
Eligibility criteria for esophageal adenocarcinoma trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
2
Phase 2
4
Top Sponsors
Boehringer Ingelheim 1 trial
Plexium, Inc. 1 trial
Gilead Sciences 1 trial
VA Office of Research and Development 1 trial
National Cancer Institute (NCI) 1 trial

Recruiting Clinical Trials

NCT06324357 Phase 1, Phase 2
Recruiting
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
Enrollment
768 pts
Location
United States, Belgi...
Sponsor
Boehringer Ingelheim
View Trial →
NCT07284186 Phase 1
Recruiting
First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors
Enrollment
155 pts
Location
United States
Sponsor
Plexium, Inc.
View Trial →
NCT07546812 Phase 2
Recruiting
Study of Denikitug (GS-1811) Given Alone or With Nivolumab or Chemotherapy in Adults With Metastatic Gastric, Gastroesophageal Junction (GEJ), and Esophageal Adenocarcinomas
Enrollment
120 pts
Location
United States, Austr...
Sponsor
Gilead Sciences
View Trial →
NCT05563766 Phase 2
Recruiting
A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer
Enrollment
78 pts
Location
United States
Sponsor
VA Office of Research and Deve...
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NCT04939051 Phase 2
Recruiting
Obeticholic Acid for Prevention in Barrett's Esophagus
Enrollment
30 pts
Location
United States
Sponsor
National Cancer Institute (NCI...
View Trial →

Related Conditions

esophageal squamous cell carcinoma (2) gastric adenocarcinoma (2) metastatic breast cancer (1) metastatic gastric adenocarcinoma (1) gastroesophageal junction adenocarcinoma (1) colorectal cancer (1) gastric squamous cell carcinoma (1) gastroesophageal junction gej adenocarcinoma (1) metastatic solid tumor (1) non small cell lung carcinoma (1) smarca4 mutation (1) gastroesophageal junction squamous cell carcinoma (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology