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diffuse midline glioma h3 k27m mutant

Total Trials
4
Recruiting Now
4
Trial Phases
Phase 1, Phase 2

ClinicalMetric tracks all active clinical trials for diffuse midline glioma h3 k27m mutant sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — diffuse midline glioma h3 k27m mutant Clinical Trials

How many clinical trials are currently recruiting for diffuse midline glioma h3 k27m mutant?
ClinicalMetric currently tracks 4 actively recruiting clinical trials for diffuse midline glioma h3 k27m mutant, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 4. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for diffuse midline glioma h3 k27m mutant?
diffuse midline glioma h3 k27m mutant research spans Phase 1 (2 trials), Phase 2 (2 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a diffuse midline glioma h3 k27m mutant clinical trial?
Eligibility criteria for diffuse midline glioma h3 k27m mutant trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
2
Phase 2
2
Top Sponsors
Emory University 1 trial
OX2 Therapeutics 1 trial
Guangzhou Virotech Pharmaceutical Co., Ltd. 1 trial
Rigel Pharmaceuticals 1 trial

Recruiting Clinical Trials

NCT06624371 Phase 1
Recruiting

Atovaquone Combined With Radiation in Children With Malignant Brain Tumors

Enrollment
18 pts
Location
United States
Sponsor
Emory University
View Trial →
NCT06305910 Phase 1
Recruiting

CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young Adults

Enrollment
24 pts
Location
United States
Sponsor
OX2 Therapeutics
View Trial →
NCT07589257 Phase 2
Recruiting

A Study of VRT106 in Combination With Radiotherapy in Adult Patients With Diffuse Midline Glioma / Diffuse Intrinsic Pontine Glioma

Enrollment
10 pts
Location
China
Sponsor
Guangzhou Virotech Pharmaceuti...
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NCT06161974 Phase 2
Recruiting

Study of Olutasidenib and Temozolomide in HGG

Enrollment
60 pts
Location
United States, Austr...
Sponsor
Rigel Pharmaceuticals
View Trial →
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology