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high grade glioma

Total Trials
9
Recruiting Now
9
Trial Phases
Phase 1, Phase 2, EARLY_Phase 1, Phase 1

ClinicalMetric tracks all active clinical trials for high grade glioma sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — high grade glioma Clinical Trials

How many clinical trials are currently recruiting for high grade glioma?
ClinicalMetric currently tracks 9 actively recruiting clinical trials for high grade glioma, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 9. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for high grade glioma?
high grade glioma research spans Phase 1 (5 trials), Phase 2 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a high grade glioma clinical trial?
Eligibility criteria for high grade glioma trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
5
Phase 2
1
Top Sponsors
Maastricht Radiation Oncology 1 trial
Laminar Pharmaceuticals 1 trial
NYU Langone Health 1 trial
Beijing Biotech 1 trial
Eben Rosenthal 1 trial

Recruiting Clinical Trials

NCT04865315
Recruiting
A Living Tissue Bank of Patient-Derived Organoids From Glioma Tumors
Enrollment
50 pts
Location
Netherlands
Sponsor
Maastricht Radiation Oncology
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NCT04299191 Phase 1, Phase 2
Recruiting
Study of LAM561 Acid in Pediatric Patients With Malignant Glioma and Other Advanced Solid Tumors
Enrollment
28 pts
Location
United States
Sponsor
Laminar Pharmaceuticals
View Trial →
NCT06829173 EARLY_Phase 1
Recruiting
Concurrent XRD-0394 With Radiation Therapy for High Grade Gliomas
Enrollment
39 pts
Location
United States
Sponsor
NYU Langone Health
View Trial →
NCT07480941 Phase 1
Recruiting
Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma
Enrollment
36 pts
Location
China
Sponsor
Beijing Biotech
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NCT07210632 EARLY_Phase 1
Recruiting
Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG)
Enrollment
38 pts
Location
United States
Sponsor
Eben Rosenthal
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NCT05839379
Recruiting
Targeted Pediatric High-Grade Glioma Therapy
Enrollment
350 pts
Location
United States, Austr...
Sponsor
Nationwide Children's Hospital
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NCT06072586 EARLY_Phase 1
Recruiting
A Phase 0/1 Study of BDTX-1535 in Recurrent High-Grade Glioma (rHGG) and Newly Diagnosed Glioblastoma (nGBM) Participants With EGFR Alterations or Fusions
Enrollment
82 pts
Location
United States
Sponsor
St. Joseph's Hospital and Medi...
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NCT06215495
Recruiting
A Novel Target Delineation Scheme in High-grade Glioma Patients: a Randomized Single-blind Clinical Trial
Enrollment
88 pts
Location
China
Sponsor
Zhujiang Hospital
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NCT06831773
Recruiting
Clinical Study of Carbon Ion Radiotherapy for High-grade Glioma
Enrollment
23 pts
Location
China
Sponsor
Gansu Wuwei Tumor Hospital
View Trial →

Related Conditions

glioblastoma (3) low grade glioma (1) solid tumor unspecified child (1) malignant glioma (1) recurrent glioblastoma (1) recurrent high grade glioma (1) brain cancer (1) hgg (1) glioma (1) high grade gliomas (1) high grade glioma iii or iv (1) high grade glioma hgg of the brain with braf aberration (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology