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high grade glioma

Total Trials
9
Recruiting Now
9
Trial Phases
Phase 1, Phase 2, Phase 1

ClinicalMetric tracks all active clinical trials for high grade glioma sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — high grade glioma Clinical Trials

How many clinical trials are currently recruiting for high grade glioma?
ClinicalMetric currently tracks 9 actively recruiting clinical trials for high grade glioma, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 9. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for high grade glioma?
high grade glioma research spans Phase 1 (6 trials), Phase 2 (2 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a high grade glioma clinical trial?
Eligibility criteria for high grade glioma trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
6
Phase 2
2
Top Sponsors
Maastricht Radiation Oncology 1 trial
National Institute of Neurological Disorders and Stroke (NINDS) 1 trial
Gansu Wuwei Tumor Hospital 1 trial
Laminar Pharmaceuticals 1 trial
Northwell Health 1 trial

Recruiting Clinical Trials

NCT04865315
Recruiting
A Living Tissue Bank of Patient-Derived Organoids From Glioma Tumors
Enrollment
50 pts
Location
Netherlands
Sponsor
Maastricht Radiation Oncology
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NCT07416188 Phase 1, Phase 2
Recruiting
Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma
Enrollment
40 pts
Location
United States
Sponsor
National Institute of Neurolog...
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NCT06831773
Recruiting
Clinical Study of Carbon Ion Radiotherapy for High-grade Glioma
Enrollment
23 pts
Location
China
Sponsor
Gansu Wuwei Tumor Hospital
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NCT04299191 Phase 1, Phase 2
Recruiting
Study of LAM561 Acid in Pediatric Patients With Malignant Glioma and Other Advanced Solid Tumors
Enrollment
28 pts
Location
United States
Sponsor
Laminar Pharmaceuticals
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NCT05979064
Recruiting
Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM)
Enrollment
10 pts
Location
United States
Sponsor
Northwell Health
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NCT04254419 Phase 1
Recruiting
Phase 1 Study of Locoregional Injections of Ex Vivo Expanded Natural Killer Cells
Enrollment
18 pts
Location
United States
Sponsor
Nationwide Children's Hospital
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NCT05298995 Phase 1
Recruiting
GD2-CAR T Cells for Pediatric Brain Tumours
Enrollment
54 pts
Location
Italy
Sponsor
Bambino Gesù Hospital and Rese...
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NCT06428045 Phase 1
Recruiting
STARLITE for Unresectable High-Grade Gliomas
Enrollment
24 pts
Location
United States
Sponsor
University of Miami
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NCT07480941 Phase 1
Recruiting
Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma
Enrollment
36 pts
Location
China
Sponsor
Beijing Biotech
View Trial →

Related Conditions

recurrent glioblastoma (2) glioblastoma multiforme (2) glioma (2) gbm (2) glioma malignant (2) brain cancer (2) glioblastoma (2) low grade glioma (1) glioblastoma idh isocitrate dehydrogenase wildtype (1) relapsed cancer (1) recurrent tumor (1) recurring glioblastoma (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology