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anxiety disorders

Total Trials
11
Recruiting Now
11
Trial Phases
Phase 3

Anxiety disorder trials span generalized anxiety disorder (GAD), social anxiety disorder, PTSD, OCD, and panic disorder, with increasing interest in neurobiological targets beyond serotonin and GABA systems. PTSD research has been particularly active following MDMA-assisted therapy trials showing striking efficacy in Phase 3 studies.

Trials evaluate CRHR1 antagonists, V1b antagonists, cannabidiol formulations, MDMA-assisted psychotherapy, exposure-based digital therapeutics, and transcranial magnetic stimulation. PTSD trials often recruit veterans and first responders through VA and DoD partnerships.

Frequently Asked Questions — anxiety disorders Clinical Trials

How many clinical trials are currently recruiting for anxiety disorders?
ClinicalMetric currently tracks 11 actively recruiting clinical trials for anxiety disorders, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 11. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for anxiety disorders?
anxiety disorders research spans Phase 3 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a anxiety disorders clinical trial?
Eligibility criteria for anxiety disorders trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 3
1
Top Sponsors
Singula Institute 1 trial
UCLH/UCL Joint Research Office 1 trial
Dartmouth-Hitchcock Medical Center 1 trial
Shenyang Medical College 1 trial
Universitat Jaume I 1 trial

Recruiting Clinical Trials

NCT05466851
Recruiting
An Exploratory Study Examining Biopsychosocial Markers of Anxiety and Depression
Enrollment
200 pts
Location
United States
Sponsor
Singula Institute
View Trial →
NCT05549102
Recruiting
CBT and the Neural Circuits of Anxiety
Enrollment
174 pts
Location
United Kingdom
Sponsor
UCLH/UCL Joint Research Office
View Trial →
NCT06898593
Recruiting
Enhancing Engagement by Integrating Goals and Concerns That Matter to Patients
Enrollment
2,448 pts
Location
United States
Sponsor
Dartmouth-Hitchcock Medical Ce...
View Trial →
NCT07244484
Recruiting
Closed-Loop Neurofeedback Targeting the Left Dorsolateral Prefrontal Cortex for Cardiac Autonomic Modulation in Coronary Artery Disease With Anxiety
Enrollment
56 pts
Location
China
Sponsor
Shenyang Medical College
View Trial →
NCT05569018
Recruiting
Efficacy of a Transdiagnostic Group Treatment for Emotional Disorders Applied in Blended Format: a Controlled Study.
Enrollment
144 pts
Location
Spain
Sponsor
Universitat Jaume I
View Trial →
NCT06844058
Recruiting
Islamic-Oriented vs. Standard Ericksonian Hypnotherapy for Anxiety and Depression
Enrollment
90 pts
Location
Turkey (Türkiye)
Sponsor
Istanbul Nisantasi University
View Trial →
NCT07576686
Recruiting
AI-Guided CBT for Depression and Anxiety
Enrollment
120 pts
Location
Serbia
Sponsor
Aleksandra Stojanovic
View Trial →
NCT06273904
Recruiting
Modulating Escape Using Focused Ultrasound
Enrollment
40 pts
Location
United States
Sponsor
Medical University of South Ca...
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NCT03953014
Recruiting
Pharmacogenetics of Antidepressant-Induced Disinhibition
Enrollment
120 pts
Location
Canada
Sponsor
University of Calgary
View Trial →
NCT07123467 Phase 3
Recruiting
Cannabidiol-Assisted Learning for Managing Generalized Anxiety Disorder
Enrollment
90 pts
Location
United States
Sponsor
Wayne State University
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NCT07903246
Recruiting
A Prospective Study of Anxiety, Depression, and Bipolar Disorder in People
Enrollment
2,690 pts
Location
China
Sponsor
Second Affiliated Hospital, Zh...
View Trial →

Related Conditions

depressive disorder (2) depression (1) stress related disorder (1) generalised anxiety disorder (1) cbt (1) anxiety depression (1) anxiety disorders and symptoms (1) anxiety generalized (1) anxiety (1) anxiety disorder generalized (1) anxiety disorder mixed with depression mild (1) depression disorders (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology