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anxiety disorders

Total Trials
7
Recruiting Now
7
Trial Phases
Various

Anxiety disorder trials span generalized anxiety disorder (GAD), social anxiety disorder, PTSD, OCD, and panic disorder, with increasing interest in neurobiological targets beyond serotonin and GABA systems. PTSD research has been particularly active following MDMA-assisted therapy trials showing striking efficacy in Phase 3 studies.

Trials evaluate CRHR1 antagonists, V1b antagonists, cannabidiol formulations, MDMA-assisted psychotherapy, exposure-based digital therapeutics, and transcranial magnetic stimulation. PTSD trials often recruit veterans and first responders through VA and DoD partnerships.

Frequently Asked Questions — anxiety disorders Clinical Trials

How many clinical trials are currently recruiting for anxiety disorders?
ClinicalMetric currently tracks 7 actively recruiting clinical trials for anxiety disorders, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 7. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for anxiety disorders?
anxiety disorders research spans multiple clinical trial phases. Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a anxiety disorders clinical trial?
Eligibility criteria for anxiety disorders trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Top Sponsors
University of Texas at Austin 1 trial
Massachusetts General Hospital 1 trial
Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud 1 trial
Babes-Bolyai University 1 trial
Helse Stavanger HF 1 trial

Recruiting Clinical Trials

NCT05427708
Recruiting
Respiratory Training in the Treatment of Transdiagnostic Pathological Anxiety
Enrollment
180 pts
Location
United States
Sponsor
University of Texas at Austin
View Trial →
NCT06289621
Recruiting
Brief Transdiagnostic Treatment for Anxiety Disorders and Post-traumatic Stress Disorder (PTSD) in South Africa
Enrollment
60 pts
Location
South Africa
Sponsor
Massachusetts General Hospital
View Trial →
NCT06833567
Recruiting
Mentalizing and Epistemic Trust in Patients With Anxiety and Depression.
Enrollment
100 pts
Location
Spain
Sponsor
Fundación Pública Andaluza par...
View Trial →
NCT06724666
Recruiting
Transdiagnostic Internet-delivered Intervention for Adolescents With Anxiety and Depression
Enrollment
198 pts
Location
Romania
Sponsor
Babes-Bolyai University
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NCT07145307
Recruiting
Personalized Digital Treatment for Adolescent Anxiety: A Feasibility Trial
Enrollment
46 pts
Location
Norway
Sponsor
Helse Stavanger HF
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NCT07100951
Recruiting
Comparing Brief Psychoanalytic Couple Therapy and Emotionally Focused Therapy in Reducing Relationship Distress
Enrollment
120 pts
Location
Turkey (Türkiye)
Sponsor
Beykoz University
View Trial →
NCT06763081
Recruiting
Pharmacogenomics of Selective Serotonin Reuptake Inhibitor (SSRI)-Induced Behavioural Activation
Enrollment
160 pts
Location
Canada
Sponsor
University of Manitoba
View Trial →

Related Conditions

generalized anxiety disorder (2) social anxiety disorder (2) depressive disorder (2) major depressive disorder (2) trauma (1) panic disorder (1) agoraphobia (1) illness anxiety disorder (1) posttraumatic stress disorder (1) acute stress disorder (1) adjustment disorder with anxious mood (1) post traumatic stress disorder (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology