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Recruiting NCT05724433

NCT05724433 VIrtual Care To Improve Outcomes and RecoverY From Heart Failure Hospitalization

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Clinical Trial Summary
NCT ID NCT05724433
Status Recruiting
Phase
Sponsor Population Health Research Institute
Condition Heart Failure
Study Type INTERVENTIONAL
Enrollment 891 participants
Start Date 2023-01-23
Primary Completion 2025-12-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Virtual HF CareRoutine HF Care

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 891 participants in total. It began in 2023-01-23 with a primary completion date of 2025-12-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The clinic visits (intervention) will continue for 90 days, which represents the follow-up period for the primary medication and health status outcomes. The co-primary clinical outcomes will be obtained at 180 days.

Eligibility Criteria

Inclusion Criteria: Adult patients ≥ 18 years old who: 1. Are being discharged after hospitalization or urgent visit for HF as 1. a primary diagnosis or 2. significant complication (prolonging length of stay) of another diagnosis OR Have been referred for an initial consult at a cardiology clinic within 1 week of hospitalization or urgent visit for HF as a primary or secondary diagnosis, as described above. 2. Have left ventricular ejection fraction (LVEF) \< 50% within the preceding 3 months. 3. Have NT-proBNP of \> 900 pg/ml during hospital admission or within 7 days after discharge from the ED 4. Have a mailing address for patient or caregiver 5. Provide verbal consent Exclusion Criteria: 1. Died or left hospital before medically advised hospital discharge 2. Unable to self-assess or communicate symptoms (e.g. clinically evident dementia) 3. Unable to engage with digital health technology or follow up 4. Severe valve disease 5. Recipient of or on waiting list for LVAD or cardiac transplant 6. Complex congenital heart disease, hypertrophic obstructive cardiomyopathy, or amyloid cardiomyopathy 7. Severe lung disease with symptoms on minimal exertion, forced expiratory volume during 1 second (FEV1) \< 1 litre, severe pulmonary hypertension with RVSP \> 60 mm Hg, or on home oxygen 8. Severe kidney disease (persistent eGFR \< 30 mL/min/1.73m2) 9. Active malignancy 10. Receiving palliative care or expected life expectancy \< 6 months

Contact & Investigator

Central Contact

Harriette GC Van Spall, MD MPH

✉ Harriette.VanSpall@phri.ca

📞 (905) 521-2100

Principal Investigator

Harriette Van Spall, MD

PRINCIPAL INVESTIGATOR

McMaster University

Frequently Asked Questions

Who can join the NCT05724433 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Heart Failure. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05724433 currently recruiting?

Yes, NCT05724433 is actively recruiting participants. Contact the research team at Harriette.VanSpall@phri.ca for enrollment information.

Where is the NCT05724433 trial being conducted?

This trial is being conducted at Hamilton, Canada, Hamilton, Canada, Hamilton, Canada, Thunder Bay, Canada and 5 additional locations.

Who is sponsoring the NCT05724433 clinical trial?

NCT05724433 is sponsored by Population Health Research Institute. The principal investigator is Harriette Van Spall, MD at McMaster University. The trial plans to enroll 891 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology