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Recruiting NCT06446661

NCT06446661 Using Text Messages to Improve Oral Chemotherapy for Adolescents and Adults With Acute Lymphoblastic Leukemia

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Clinical Trial Summary
NCT ID NCT06446661
Status Recruiting
Phase
Sponsor University of Chicago
Condition Acute Lymphoblastic Leukemia
Study Type INTERVENTIONAL
Enrollment 48 participants
Start Date 2026-05-19
Primary Completion 2027-06-15

Eligibility & Interventions

Sex All sexes
Min Age 15 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
High IntensityNo Text MessagingsLow Intensity Text Messaging

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 48 participants in total. It began in 2026-05-19 with a primary completion date of 2027-06-15.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This is a single center 2-phase study to assess effects of using text messages on adherence to oral chemotherapy for patients with acute lymphoblastic leukemia (ALL) or T-cell lymphoblastic lymphoma.

Eligibility Criteria

Inclusion Criteria: * Age of 15 years or older at time of enrollment * Diagnosed with ALL or T-cell lymphoblastic lymphoma * Currently receiving treatment with pediatric-based regimen that includes maintenance with mercaptopurine and methotrexate (e.g., CALGB 10403). Study participation begins with the start of maintenance, so enrollment occurs prior to the start of maintenance. Patients in the pilot phase may have already started maintenance as long as the end of their maintenance therapy is scheduled to occur after the end of the 28-day pilot intervention. Exclusion Criteria: * Patient or caregiver who would receive text message reminders does not have a cell phone that receives text messages * Patient does not wish to participate * Text messages will be crafted in the patient's preferred language for medical communication, so English fluency is not an enrollment requirement.

Contact & Investigator

Central Contact

Clinical Trials Intake

✉ cancerclinicaltrials@bsd.uchicago.edu

📞 1-855-702-8222

Principal Investigator

Austin Wesevich

PRINCIPAL INVESTIGATOR

University of Chicago

Frequently Asked Questions

Who can join the NCT06446661 clinical trial?

This trial is open to participants of all sexes, aged 15 Years or older, studying Acute Lymphoblastic Leukemia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06446661 currently recruiting?

Yes, NCT06446661 is actively recruiting participants. Contact the research team at cancerclinicaltrials@bsd.uchicago.edu for enrollment information.

Where is the NCT06446661 trial being conducted?

This trial is being conducted at Chicago, United States.

Who is sponsoring the NCT06446661 clinical trial?

NCT06446661 is sponsored by University of Chicago. The principal investigator is Austin Wesevich at University of Chicago. The trial plans to enroll 48 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology