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Recruiting NCT06710665

NCT06710665 Tumor Regression Grade As Predictor of Adjuvant Therapy

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Clinical Trial Summary
NCT ID NCT06710665
Status Recruiting
Phase
Sponsor Fujian Medical University Union Hospital
Condition Esophageal Squamous Cell Carcinoma (ESCC)
Study Type OBSERVATIONAL
Enrollment 400 participants
Start Date 2024-10-01
Primary Completion 2025-10-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Chemotherapy

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 400 participants in total. It began in 2024-10-01 with a primary completion date of 2025-10-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Neoadjuvant therapy followed by surgery is preferred for locally advanced esophageal squamous cell carcinoma, but the necessity of adjuvant therapy remains controversial. Tumor regression grade reflects the response to neoadjuvant therapy and may predict patient prognosis, yet its role in guiding adjuvant therapy remains unexplored.

Eligibility Criteria

Inclusion Criteria: (I) underwent R0 resection with either two-field or three-field lymphadenectomy (II) received neoadjuvant therapy such as preoperative radiotherapy, chemoradiotherapy, or combined immunotherapy (III) had esophageal squamous cell carcinoma pathology. Exclusion Criteria: (I) Patients with incomplete clinical data or follow-up information (II) Diagnosed with multiple primary malignancies

Contact & Investigator

Central Contact

Maohui Chen

✉ 757860733@qq.com

📞 18659181171

Principal Investigator

Bin Zheng

STUDY DIRECTOR

Key Laboratory of Cardio-Thoracic Surgery, Fujian Medical University, Fujian Province University, Fu

Frequently Asked Questions

Who can join the NCT06710665 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Esophageal Squamous Cell Carcinoma (ESCC). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06710665 currently recruiting?

Yes, NCT06710665 is actively recruiting participants. Contact the research team at 757860733@qq.com for enrollment information.

Where is the NCT06710665 trial being conducted?

This trial is being conducted at Fuzhou, China.

Who is sponsoring the NCT06710665 clinical trial?

NCT06710665 is sponsored by Fujian Medical University Union Hospital. The principal investigator is Bin Zheng at Key Laboratory of Cardio-Thoracic Surgery, Fujian Medical University, Fujian Province University, Fu. The trial plans to enroll 400 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology