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Recruiting NCT06381531

Tracing Brain Tumors Through Deep Time

Trial Parameters

Condition Brain Tumor
Sponsor Tata Memorial Centre
Study Type OBSERVATIONAL
Phase N/A
Enrollment 10,000
Sex ALL
Min Age N/A
Max Age N/A
Start Date 2025-01-10
Completion 2027-06-10
Interventions
Imaging with CT and MRI

Brief Summary

Brain tumors involve different age groups with a wide range of tumor types involving different anatomical compartments of the brain. The evolution of the brain in vertebrates, including the most recent homo species (including humans), has occurred through increasing structural complexity in more evolved species. In the retrospective study, we will investigate the location of the tumors and different structural aspects of skull anatomy in patients with brain tumors. The information will be compared with the anatomical evolution of the brain and skull in vertebrates to look for possible associations, which can provide insights into evolutionary biology.

Eligibility Criteria

Inclusion Criteria: • All patients diagnosed with primary brain tumors with available pre/ post-operative or pre-radiation brain images with computed tomography (CT) or magnetic resonance imaging (MRI) Exclusion Criteria: * CT/ MRI is not available before cranial radiotherapy * Artifacts causing distortion of skull (bony) anatomy

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