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Recruiting NCT06580106

NCT06580106 Toxicity Genetic Determinants and Response to Azacitidine and Venetoclax in AML

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Clinical Trial Summary
NCT ID NCT06580106
Status Recruiting
Phase
Sponsor Wake Forest University Health Sciences
Condition Leukemia, Myeloid, Acute
Study Type OBSERVATIONAL
Enrollment 50 participants
Start Date 2025-04-09
Primary Completion 2027-07

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Biospecimen samples

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 50 participants in total. It began in 2025-04-09 with a primary completion date of 2027-07.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of this research is to see how certain genetic variations relate to side effects and outcomes experienced while receiving treatment with azacitidine and venetoclax.

Eligibility Criteria

Inclusion Criteria: * Written informed consent and HIPAA authorization for release of personal health information. * Age ≥ 18 years of age at the time of consent * Confirmed diagnosis of AML * Planned initial treatment with azacitidine and venetoclax * Ability to read and understand the English and/or Spanish language * As determined by the enrolling investigator, ability of the participant to understand and comply with study procedures for the entire length of the study Exclusion Criteria: * None

Contact & Investigator

Central Contact

Courtney Schepel

✉ courtney.schepel@advocatehealth.org

📞 (980) 292-0817

Principal Investigator

Brittany Ragon, MD

PRINCIPAL INVESTIGATOR

Atrium Health Wake Forest Baptist Comprehensive Cancer Center

Frequently Asked Questions

Who can join the NCT06580106 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Leukemia, Myeloid, Acute. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06580106 currently recruiting?

Yes, NCT06580106 is actively recruiting participants. Contact the research team at courtney.schepel@advocatehealth.org for enrollment information.

Where is the NCT06580106 trial being conducted?

This trial is being conducted at Charlotte, United States, Winston-Salem, United States.

Who is sponsoring the NCT06580106 clinical trial?

NCT06580106 is sponsored by Wake Forest University Health Sciences. The principal investigator is Brittany Ragon, MD at Atrium Health Wake Forest Baptist Comprehensive Cancer Center. The trial plans to enroll 50 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology