NCT07623590 Titration of Positive End-expiratory Pressure: Comparison Between Manual Thoracic or Abdominal Compression and Electrical Impedance Tomography
| NCT ID | NCT07623590 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Centre Hospitalier Saint Joseph Saint Luc de Lyon |
| Condition | ARDS (Acute Respiratory Distress Syndrome) |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2025-04-07 |
| Primary Completion | 2027-05-05 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2025-04-07 with a primary completion date of 2027-05-05.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Patients with acute respiratory distress syndrome are placed on mechanical ventilation, and the adjustment of ventilator parameters is an important step in their care, in particular positive expiratory pressure, applied at the end of breathing. The goal of this study is to learn if continuous anterior chest compression works as well as electrical impedance tomography for positive expiratory pressure titration. Researchers will compare the two methods for each patient, in a randomly determined order : continuous anterior chest compression and electrical impedance tomography. Participants will : * have a pep titration with both techniques * be included in the study for 28 days
Eligibility Criteria
Inclusion Criteria: * Age ≥ 18 years * Moderate to severe ARDS according to the Berlin criteria * Patient receiving sedation and continuous curarization * Free and informed consent from the patient or their loved one Exclusion Criteria: * ECMO * Pneumothorax * Chest trauma in the last 3 months * Uncontrolled shock (noradrenaline \> 5 mg/h) * Pregnant or breastfeeding woman * Protected adult within the meaning of the law * Lack of social security * Patient under AME
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07623590 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying ARDS (Acute Respiratory Distress Syndrome). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07623590 currently recruiting?
Yes, NCT07623590 is actively recruiting participants. Contact the research team at evivier@saintjosephsaintluc.fr for enrollment information.
Where is the NCT07623590 trial being conducted?
This trial is being conducted at Créteil, France, Lyon, France.
Who is sponsoring the NCT07623590 clinical trial?
NCT07623590 is sponsored by Centre Hospitalier Saint Joseph Saint Luc de Lyon. The trial plans to enroll 30 participants.