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Recruiting NCT06508866

NCT06508866 Timing And Typology of ConducTIon disturbanCes During TAVI

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Clinical Trial Summary
NCT ID NCT06508866
Status Recruiting
Phase
Sponsor Istituto Clinico Humanitas
Condition Aortic Stenosis, Severe
Study Type OBSERVATIONAL
Enrollment 490 participants
Start Date 2023-02-01
Primary Completion 2024-12-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 490 participants in total. It began in 2023-02-01 with a primary completion date of 2024-12-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The TACTIC-TAVI registry aims to collect information about a consecutive cohort of patients undergoing transcatheter aortic valve insertion. The registry is international, multi-centre and observational. The registry is planned to continue until the calculated sample size is achieved.

Eligibility Criteria

Inclusion Criteria: Patients successfully undergoing transcatheter aortic valve implantation for native severe aortic stenosis. \- Exclusion Criteria: 1. Presence of previously implanted permanent cardiac pacemaker. 2. Valve-in-valve procedures. 3. No pre-procedural electrocardiogram is available. 4. No pre-procedural contrast CT TAVI is available. 5. Enrollment in another clinical trial. 6. Patients aged less than 18 years old. 7. Patients who do not consent for their data to be included in the registry. 8. Failed transcatheter aortic valve deployment. -

Contact & Investigator

Central Contact

Antonio Mangieri, MD

✉ antonio.mangieri@humanitas.it

📞 0282243084

Principal Investigator

Antonio Mangieri, MD

PRINCIPAL INVESTIGATOR

Humanitas Research Horspital

Frequently Asked Questions

Who can join the NCT06508866 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Aortic Stenosis, Severe. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06508866 currently recruiting?

Yes, NCT06508866 is actively recruiting participants. Contact the research team at antonio.mangieri@humanitas.it for enrollment information.

Where is the NCT06508866 trial being conducted?

This trial is being conducted at Rozzano, Italy.

Who is sponsoring the NCT06508866 clinical trial?

NCT06508866 is sponsored by Istituto Clinico Humanitas. The principal investigator is Antonio Mangieri, MD at Humanitas Research Horspital. The trial plans to enroll 490 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology