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Recruiting NCT06922162

NCT06922162 Tickle Stimulation in Disorders of Consciousness (DoC)

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Clinical Trial Summary
NCT ID NCT06922162
Status Recruiting
Phase
Sponsor Anna Estraneo
Condition Disorders of Consciousness
Study Type OBSERVATIONAL
Enrollment 45 participants
Start Date 2023-06-30
Primary Completion 2025-07-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Tickle stimulationNeurophysiological Monitoring with SedLine

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 45 participants in total. It began in 2023-06-30 with a primary completion date of 2025-07-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The aim of this project is to investigate whether tickling stimulations can have a short-term effect on the responsiveness of patients with Disorders of Consciousness due to Severe Acquired Brain Injury and to compare this effect with that of neutral tactile stimulations that do not induce tickling.

Eligibility Criteria

Inclusion Criteria: * Diagnosis of disorders of consciousness (DoC) based on the CRS-R scale; * Age ≥18 years; * Time since the event ≥ 28 days Exclusion Criteria: * Large craniectomy that may interfere with fNIRS recording; Unstable clinical conditions (e.g., respiratory failure, fever, status epilepticus, etc.); * Fractures, paralysis, injuries, or muscular dystrophy that prevent proper stimulation of the aforementioned body parts; * Lack of informed consent from the legal representative.

Contact & Investigator

Central Contact

Simona Abagnale, PhD

✉ sabagnale@dongnocchi.it

📞 +393487520258

Principal Investigator

Anna Estraneo, MD

PRINCIPAL INVESTIGATOR

Fondazione Don Gnocchi

Frequently Asked Questions

Who can join the NCT06922162 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Disorders of Consciousness. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06922162 currently recruiting?

Yes, NCT06922162 is actively recruiting participants. Contact the research team at sabagnale@dongnocchi.it for enrollment information.

Where is the NCT06922162 trial being conducted?

This trial is being conducted at Liège, Belgium, Sant'Angelo dei Lombardi, Italy.

Who is sponsoring the NCT06922162 clinical trial?

NCT06922162 is sponsored by Anna Estraneo. The principal investigator is Anna Estraneo, MD at Fondazione Don Gnocchi. The trial plans to enroll 45 participants.

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