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Recruiting NCT05598645

NCT05598645 Thulium Fiber Laser (TFL) Versus Holmium MOSES Laser for Ureteroscopic Management of Kidney Stones

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Clinical Trial Summary
NCT ID NCT05598645
Status Recruiting
Phase
Sponsor Thunder Bay Regional Health Research Institute
Condition Kidney Stone
Study Type INTERVENTIONAL
Enrollment 174 participants
Start Date 2022-08-16
Primary Completion 2026-06

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Thulium Fibre LaserMOSES Holmium Laser

Eligibility Fast-Check

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What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 174 participants in total. It began in 2022-08-16 with a primary completion date of 2026-06.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study aims to compare the efficacy and safety of both types of lasers, Holmium MOSES and TFL, in management of kidney stones requiring treatment.

Eligibility Criteria

Inclusion Criteria: 1. 18 years of age and over at the time of enrollment. 2. Patients referred with single kidney stones of 10-20 mm in its largest diameter, or multiple stones involving a single calyx. 3. Written informed consent to participate in the study 4. Ability to comply with the requirements of the study procedures Exclusion Criteria: 1. Patients with ipsilateral distal ureteral stones or stricture. 2. Stone size \> 20 mm or multiple kidney stones in different calyces. 3. Previous shock wave lithotripsy (SWL) treatment for the same stone. 4. Participants with active urinary tract infection until appropriately treated 5. Uncorrected coagulopathy (anticoagulants or blood thinners which cannot be withheld before surgery). 6. Pregnancy. 7. Participants with preexisting conditions, which, in the opinion of the investigator, interfere with the conduct of the study. 8. Participants who are uncooperative or cannot follow instructions. 9. Participants who lack the capacity, or cannot speak English, in order to provide free and informed written consent. 10. Patients with solitary kidney.

Contact & Investigator

Central Contact

Shalyn Littlefield, MSc

✉ shalyn.littlefield@tbh.net

📞 (807) 684-6000

Principal Investigator

Hazem Elmansy, MD

PRINCIPAL INVESTIGATOR

Urologist

Frequently Asked Questions

Who can join the NCT05598645 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Kidney Stone. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05598645 currently recruiting?

Yes, NCT05598645 is actively recruiting participants. Contact the research team at shalyn.littlefield@tbh.net for enrollment information.

Where is the NCT05598645 trial being conducted?

This trial is being conducted at Thunder Bay, Canada.

Who is sponsoring the NCT05598645 clinical trial?

NCT05598645 is sponsored by Thunder Bay Regional Health Research Institute. The principal investigator is Hazem Elmansy, MD at Urologist. The trial plans to enroll 174 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology