NCT06929364 The Role of Probiotics in the Treatment of Endometriosis (ProMetrioS): a Randomised Double-blinded Placebo-controlled Cross-over Trial
| NCT ID | NCT06929364 |
| Status | Recruiting |
| Phase | — |
| Sponsor | The Gut Microbiome Center (Centar za crijevni mikrobiom) |
| Condition | Endometriosis |
| Study Type | INTERVENTIONAL |
| Enrollment | 40 participants |
| Start Date | 2024-11-01 |
| Primary Completion | 2025-05-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 40 participants in total. It began in 2024-11-01 with a primary completion date of 2025-05-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
ProMetrioS is a randomised blinded placebo-controlled cross-over trial investigating the effect of specific multistrain probiotics in patients with endometriosis. The aim of this clinical trial is to determine whether probiotic treatment can significantly modulate gut microbiome composition and functionality in endometriosis patients, specifically parameters associated with the estrobolome.
Eligibility Criteria
Minimum Age: - Maximum Age: 35 Years Sex: Female Gender Based: Ye - only women can participate in this study Accepts Healthy Volunteers: No Inclusion Criteria: * adult subjects with stage III or IV endometriosis diagnosis confirmed by biopsy Exclusion Criteria: * Age \> 35 years * Immunocompromised patients * Patients with chronic inflammatory diseases (e.g., autoimmune disorders) * Pregnancy * Use of supplements and foods with probiotics * Use of immunosuppressant, antibiotic, proton pump inhibitors and corticosteroid drugs * Use of probiotics product less than one month before start of study or during study
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06929364 clinical trial?
This trial is open to female participants only, up to 35 Years, studying Endometriosis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06929364 currently recruiting?
Yes, NCT06929364 is actively recruiting participants. Contact the research team at ira.renko@gmail.com for enrollment information.
Where is the NCT06929364 trial being conducted?
This trial is being conducted at Zagreb, Croatia.
Who is sponsoring the NCT06929364 clinical trial?
NCT06929364 is sponsored by The Gut Microbiome Center (Centar za crijevni mikrobiom). The trial plans to enroll 40 participants.