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Recruiting NCT06580639
The Role of a Mycobacterium Growth Inhibition Assay to Quantify Host Immune Control of M. Tuberculosis
Trial Parameters
Condition Tuberculosis
Sponsor Linkoeping University
Study Type OBSERVATIONAL
Phase N/A
Enrollment 280
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2020-08-01
Completion 2025-03-01
All Conditions
Interventions
No intervention.
Brief Summary
The goal of this observational study is to learn about how the blood leucocytes from patients with and without exposure or disease from tuberculosis (TB) are able to kill live mycobacteria (M. tuberculosis). The main question it aims to answer is: Is intracellular growth suppression of M. tuberculosis in peripheral blood mononuclear cells variable among healthy blood donors and higher than in patients with latent TB compared to active TB?
Eligibility Criteria
Inclusion Criteria: Healthy blood donors or subjects who will get vaccinated. Exclusion Criteria:Known HIV infection, not Swedish citizen, chronic liver och kidney disease,immunosuppression from treatment or disease.
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