| NCT ID | NCT07176624 |
| Status | Recruiting |
| Phase | — |
| Sponsor | The First Hospital of Jilin University |
| Condition | ARDS (Moderate or Severe) |
| Study Type | INTERVENTIONAL |
| Enrollment | 259 participants |
| Start Date | 2025-09-14 |
| Primary Completion | 2027-08-20 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 259 participants in total. It began in 2025-09-14 with a primary completion date of 2027-08-20.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
During the prone position, there may be an increase in intragastric pressure. The investigators focus on a scientific question: Whether reducing enteral nutrition before the prone position will benefit patients with severe mechanically ventilated acute respiratory distress syndrome (ARDS). The experimental group had the enteral nutrition dose reduced before the prone position, while the control group did not have the enteral nutrition dose reduced
Eligibility Criteria
Inclusion Criteria: * Age ≥18 years old * Within 24 hours of admission to the ICU, one or more organ systems have failed (the Sequential Organ Failure Assessment (SOFA) score of any single organ system is ≥2) * Meet the diagnostic criteria for moderate/severe ARDS (even after optimizing the ventilation Settings, the oxygenation index is still \< 150mmHg and PEEP is still ≥5 cm H2O) * It is expected to stay in the ICU for more than 48 hours Exclusion Criteria: * There are contraindications for the prone position * There are contraindications for EN, preventing the initiation of early EN (≤48 hours) * Expected to die within 48 hours * Pregnancy
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07176624 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying ARDS (Moderate or Severe). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07176624 currently recruiting?
Yes, NCT07176624 is actively recruiting participants. Contact the research team at wangyq20@mails.jlu.edu.cn for enrollment information.
Where is the NCT07176624 trial being conducted?
This trial is being conducted at Changchun, China.
Who is sponsoring the NCT07176624 clinical trial?
NCT07176624 is sponsored by The First Hospital of Jilin University. The trial plans to enroll 259 participants.